About: Oxidopamine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Oxidopamine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Oxidopamine
PubMedID_Primary_Reference
  • 2511086
NSC_Code
  • 233898
UMLS_CUI
  • C0085196
CAS_Registry
  • 1199-18-4
FDA_UNII_Code
  • 8HW4YBZ748
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 41295
PDQ_Closed_Trial_Search_ID
  • 41295
Chemical_Formula
  • C8H11NO3
Legacy_Concept_Name
  • _6-Hydroxydopamine
FULL_SYN
  • OxidopamineSYDTPNSC0233898
  • OxidopaminePTNCI
  • 5-(2-Aminoethyl)-1,2,4-benzenetriolSNNCI
  • 5-(2-Aminoethyl)-1,2,4-benzenetriolPTDCP00640
  • 6-OHDAABNCI
  • 6-HydroxydopamineSYNCI
  • 2,4,5-TrihydroxyphenethylamineSNNCI
  • OXIDOPAMINEPTFDA8HW4YBZ748
DEFINITION
  • An antagonist of the neurotransmitter dopamine with potential antineoplastic activity. 6-Hydroxydopamine (6-HOD) can be taken up by selective adrenergic terminals, thereby causing acute degeneration of adrenergic terminals that leads to depletion of norepinephrine, and of dopamine in the dopamine-sensitive sites. This agent is auto-oxidated at physiological pH that leads to the formation of reactive free radicals, thereby leading to cytotoxicity in neural cells. 6-Hydroxydopamine is often used to induce CNS and sympathetic neural lesions that model aging and various nervous disorders in animal systems.NCI
code
  • C1316
sameAs
http://linked.open...y/mesh/hasConcept
is sameAs of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software