About: PEG-interleukin-2     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • PEG-interleukin-2
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • PEG-interleukin-2
UMLS_CUI
  • C0083036
PDQ_Open_Trial_Search_ID
  • 39577
PDQ_Closed_Trial_Search_ID
  • 39577
Legacy_Concept_Name
  • PEG-interleukin-2
FULL_SYN
  • Polyethylene Glycol-Modified Recombinant Interleukin-2SYNCI
  • PEG-interleukin-2PTNCI
  • PEG-IL-2ABNCI
DEFINITION
  • A complex of polyethylene glycol conjugated with human recombinant cytokine interleukin-2 (IL-2) with antineoplastic activity. PEG-interleukin-2 induces natural killer (NK) cell activity and the production of interferon-gamma (IFN-gamma), and enhances T cell-mediated cytotoxicity. Pegylation of IL-2 protects the cytokine from degradation. (NCI04)NCI
code
  • C1304
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