About: Lymphokine-Activated Killer Cells     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Lymphokine-Activated Killer Cells
rdfs:subClassOf
Semantic_Type
  • Cell
  • Pharmacologic Substance
Preferred_Name
  • Lymphokine-Activated Killer Cells
UMLS_CUI
  • C0022687
Accepted_Therapeutic_Use_For
  • Adoptive immunotherapy
In_Clinical_Trial_For
  • Metastatic melanoma
ALT_DEFINITION
  • White blood cells that are stimulated in a laboratory to kill tumor cells.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 40219
PDQ_Closed_Trial_Search_ID
  • 40219
Legacy_Concept_Name
  • Lymphokine-Activated_Killer_Cell
FULL_SYN
  • Lymphokine Activated Killer CellSYNCI
  • Lymphokine-Activated Killer CellsPTNCI
  • Therapeutic Lymphokine-Activated Killer CellsSYNCI
  • lymphokine-activated killer cellPTNCI-GLOSSCDR0000045287
  • LAK cellPTNCI-GLOSSCDR0000044436
  • LAK CellsSYNCI
  • Cells, LAKSYNCI
DEFINITION
  • Killer cell lymphocytes activated in the presence of interleukin-2 (IL-2). Lymphokine-activated killer cells (LAKs) are cytotoxic effector cells with an exceptionally wide target cell spectrum including normal and malignant cells of different origins. LAK cells exhibit a profound heterogeneity with regard to phenotype surface marker expression; it remains to be determined if they represent a unique cell lineage.NCI
code
  • C13008
http://linked.open...y/mesh/hasConcept
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