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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Thymopentin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Thymopentin
NSC_Code
  • 645363
UMLS_CUI
  • C0080225
CAS_Registry
  • 69558-55-0
FDA_UNII_Code
  • O3Y80ZF13F
Contributing_Source
  • FDA
ALT_DEFINITION
  • Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. It is an immunomodulator which has been studied for possible use in the treatment of rheumatoid arthritis, AIDS, and other primary immunodeficiencies.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 41655
PDQ_Closed_Trial_Search_ID
  • 41655
Chemical_Formula
  • C30H49N9O9
Legacy_Concept_Name
  • Thymopentin
FULL_SYN
  • ThymopentinSYDTPNSC0645363
  • ThymopentinPTNCI
  • SintomodulinaFBNCI
  • MepentilSYDTPNSC0000975
  • ImmunoxBRNCI
  • TimunoxFBNCI
  • MepentilFBNCI
  • N-(N-(N-(N(2)-L-Arginyl-L-Lysyl)-L-alpha-Aspartyl)-L-Valyl)-L-TyrosineSNNCI
  • ORF-15244CNNCI
  • N-[N-[N-(N{2}-L-Arginyl-L-lysyl)-L-alpha-aspartyl]-L-valyl]-L-tyrosinePTDCP01050
  • THYMOPENTINPTFDAO3Y80ZF13F
DEFINITION
  • A synthetic pentapeptide which is the active site of the naturally occurring hormone thymopoietin with immunomodulating properties. Thymopentin enhances the production of thymic T cells and may help restore immunocompetence in immunosuppressed subjects. This agent also augments the effects of ionizing radiation by arresting cancer cells in the G2/M phase of the cell cycle. (NCI04)NCI
code
  • C1294
sameAs
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