About: Tributyrin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tributyrin
equivalentClass
Concept_In_Subset
Semantic_Type
  • Lipid
  • Pharmacologic Substance
Preferred_Name
  • Tributyrin
NSC_Code
  • 661583
UMLS_CUI
  • C0077025
CAS_Registry
  • 60-01-5
FDA_UNII_Code
  • S05LZ624MF
Contributing_Source
  • FDA
ALT_DEFINITION
  • A triglyceride drug that may inhibit cell growth and induce cell differentiation. Differentiating agents may be effective in changing cancer cells back into normal cells.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42290
PDQ_Closed_Trial_Search_ID
  • 42290
Chemical_Formula
  • C15H26O6
Legacy_Concept_Name
  • Tributyrin
FULL_SYN
  • TributyrinPTNCI
  • Butanoic Acid, 1,2,3-Propanetriyl EsterPTDCP04044
  • tributyrinPTNCI-GLOSSCDR0000045443
  • 1,2,3-TributyrylglycerolSNNCI
  • Glyceryl tributyrateSYDTPNSC0661583
  • TBABNCI
  • Butanoic Acid 1,2,3-Propanetriyl EsterSNNCI
  • 1,2,3-Propanetriyl ButanoateSNNCI
  • 1,2,3-TributyrylglycerolSYDTPNSC0661583
  • TRIBUTYRINPTFDAS05LZ624MF
  • Butyryl TriglycerideSYNCI
  • Glyceryl TributyrateSYNCI
  • TributyrinSYDTPNSC0661583
DEFINITION
  • A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate, the active metabolite of tributyrin, inhibits histone deacetylase, resulting in increased differentiation, decreased proliferation, cell cycle arrest, and apoptosis in some tumor cell lines. (NCI04)NCI
code
  • C1260
http://linked.open...y/mesh/hasConcept
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software