About: Ormaplatin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ormaplatin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Inorganic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Ormaplatin
NSC_Code
  • 363812
UMLS_CUI
  • C0076329
CAS_Registry
  • 62816-98-2
FDA_UNII_Code
  • SFK1SGY8V1
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 41211
PDQ_Closed_Trial_Search_ID
  • 41211
Chemical_Formula
  • C6H14N2.4Cl.Pt
Legacy_Concept_Name
  • Ormaplatin
FULL_SYN
  • TetraplatinSYDTPNSC0363812
  • TetraplatinSYNCI
  • tetrachloro(1,2-cyclohexanediamine-N,N')-, (OC-6-22-(trans))PlatinumSNNCI
  • ORMAPLATINPTFDASFK1SGY8V1
  • Platinum, tetrachloro(1,2-cyclohexanediamine-N,N')-, (OC-6-22-(trans))-SYDTPNSC0363812
  • OrmaplatinPTNCI
DEFINITION
  • A platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity.NCI
code
  • C1250
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