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AttributesValues
rdf:type
rdfs:label
  • Staurosporine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
Preferred_Name
  • Staurosporine
NSC_Code
  • 618487
UMLS_CUI
  • C0075193
CAS_Registry
  • 62996-74-1
FDA_UNII_Code
  • H88EPA0A3N
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that belongs to the family of drugs called alkaloids. It is being studied in the treatment of cancer.NCI-GLOSS
Chemical_Formula
  • C28H26N4O3
Legacy_Concept_Name
  • Staurosporine
CHEBI_ID
  • CHEBI:15738
FULL_SYN
  • STAUROSPORINEPTFDAH88EPA0A3N
  • 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-SNNCI
  • StaurosporinePTNCI
  • Antibiotic 230SYNCI
  • StaurosporineSYDTPNSC0618487
  • (9alpha,10beta,11beta,13alpha)-(+)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-oneSNNCI
  • staurosporinePTNCI-GLOSSCDR0000044852
  • Antibiotic AM 2282SYNCI
  • AM-2282CNNCI
  • (9alpha,10beta,11beta,13alpha)-(+)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-onePTDCP01722
  • CGP-39360CNNCI
DEFINITION
  • A cell permeable alkaloid isolated from Streptomyces staurosporeus exhibiting anti-cancer activity. Staurosporine is a potent, non-selective inhibitor of protein kinases, including protein kinase C. This agent induces apoptosis by an undetermined mechanism. (NCI)NCI
code
  • C1237
sameAs
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