About: Spiroplatin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Spiroplatin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Inorganic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Spiroplatin
NSC_Code
  • 311056
UMLS_CUI
  • C0075022
CAS_Registry
  • 74790-08-2
FDA_UNII_Code
  • H2V318W7LE
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39763
PDQ_Closed_Trial_Search_ID
  • 39763
Chemical_Formula
  • C8H18N2.O4S.Pt
Legacy_Concept_Name
  • Spiroplatin
FULL_SYN
  • SpiroplatinSYDTPNSC0311056
  • SpiroplatinPTNCI
  • Platinum, (1,1-cyclohexanedimethanamine-n,n')(sulfato(2-)-O,O')-, (sp-4-2)-SNNCI
  • TNO-6CNNCI
  • Cis-1,1-diamino-methylcyclohexane sulfato-platinumSNNCI
  • SPIROPLATINPTFDAH2V318W7LE
DEFINITION
  • A synthetic derivative of cyclohexane sulfatoplatinum with antineoplastic properties. Spiroplatin induces DNA cross-links, thereby inhibiting DNA replication and RNA and protein synthesis. Similar to other platinum compounds, this agent has been shown to be mutagenic and carcinogenic. (NCI04)NCI
code
  • C1234
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