About: Nandrolone Decanoate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Nandrolone Decanoate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Steroid
Preferred_Name
  • Nandrolone Decanoate
UMLS_CUI
  • C0068395
CAS_Registry
  • 360-70-3
Accepted_Therapeutic_Use_For
  • Anemia of renal insufficiency; Metastatic Breast Cancer
In_Clinical_Trial_For
  • HIV-associated weight loss.
FDA_UNII_Code
  • H45187T098
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 42677
PDQ_Closed_Trial_Search_ID
  • 42677
Chemical_Formula
  • C28H44O3
Legacy_Concept_Name
  • Nandrolone_Decanoate
FULL_SYN
  • Deca-DurabolinSYNCI
  • Nandrolone DecanoatePTNCI
  • NANDROLONE DECANOATEPTFDAH45187T098
DEFINITION
  • The decanoate salt form of nandrolone, an anabolic steroid analog of testosterone with androgenic, anabolic, and erythropoietin stimulating effects. Nandrolone enters the cell and binds to and activates specific nuclear androgen receptors in responsive tissue, including the prostate, seminal vesicles, scrotum, penis, larynx, hair follicles, muscle, and bone. The resulting activated hormone receptor complex translocates into the nucleus and binds to androgen response elements (ARE) in the promoter region of targeted genes, where the complex promotes gene expression necessary for maintaining male sex characteristics. Mimicking the negative feedback mechanism of testosterone, nandrolone decanoate also suppresses the secretion of luteinizing hormone (LH). Furthermore, this agent also stimulates erythropoietin production by enhancing the production of erythropoietic stimulating factors.NCI
code
  • C1172
sameAs
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