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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Hepsulfam
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Hepsulfam
NSC_Code
  • 329680
UMLS_CUI
  • C0062540
CAS_Registry
  • 96892-57-8
PDQ_Open_Trial_Search_ID
  • 39454
PDQ_Closed_Trial_Search_ID
  • 39454
Legacy_Concept_Name
  • Hepsulfam
FULL_SYN
  • 1,7-Heptanediyl Ester Sulfamic AcidSNNCI
  • Sulfamic acid, 1,7-heptanediyl esterSYDTPNSC0329680
  • HEPSULFAMSYDTPNSC0329680
  • HepsulfamPTNCI
DEFINITION
  • A bisulfamic ester which is similar in structure to busulfan and belongs to the family of drugs known as alkylsulfonate alkylating agents. Hepsulfam forms covalent linkages with nucleophilic centers in DNA, resulting in depurination, base miscoding, strand scission, DNA-DNA and DNA-protein cross-linking, and cytotoxicity. (NCI04)NCI
code
  • C1123
http://linked.open...y/mesh/hasConcept
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