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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Finasteride
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Steroid
Preferred_Name
  • Finasteride
UMLS_CUI
  • C0060389
CAS_Registry
  • 98319-26-7
FDA_UNII_Code
  • 57GNO57U7G
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to reduce the amount of male hormone (testosterone) produced by the body.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 41096
PDQ_Closed_Trial_Search_ID
  • 41096
Chemical_Formula
  • C23H36N2O2
Legacy_Concept_Name
  • Finasteride
CHEBI_ID
  • CHEBI:5062
FULL_SYN
  • FinasteridePTNCI
  • finasteridePTNCI-GLOSSCDR0000045336
  • Chibro-ProscarFBNCI
  • FinasteridePTDCP01171
  • MK 906CNNCI
  • (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamideSNNCI
  • ProscarBRNCI
  • Pro-CureFBNCI
  • FinastidFBNCI
  • PropeciaBRNCI
  • ProstideFBNCI
  • UrprosanFBNCI
  • FINASTERIDEPTFDA57GNO57U7G
  • PropeshiaFBNCI
DEFINITION
  • A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation.NCI
code
  • C1099
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