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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Exemestane
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Steroid
Preferred_Name
  • Exemestane
NSC_Code
  • 713563
UMLS_CUI
  • C0851344
CAS_Registry
  • 107868-30-4
Accepted_Therapeutic_Use_For
  • Estrogen Receptor-Positive Early Breast Cancer; early and advanced-stage breast cancer
In_Clinical_Trial_For
  • Breast cancer
FDA_UNII_Code
  • NY22HMQ4BX
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat advanced breast cancer and to prevent recurrent breast cancer in postmenopausal women who have already been treated with tamoxifen. It is also being studied in the treatment of other types of cancer. Aromasin causes a decrease in the amount of estrogen made by the body. It is a type of aromatase inhibitor.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42297
PDQ_Closed_Trial_Search_ID
  • 42297
Chemical_Formula
  • C20H24O2
Legacy_Concept_Name
  • Exemestane
CHEBI_ID
  • CHEBI:4953
FULL_SYN
  • exemestanePTNCI-GLOSSCDR0000045445
  • ExemestanePTDCP20117
  • 6-Methyleneandrosta-1,4-diene-3,17-dioneSNNCI
  • EXEMESTANEPTFDANY22HMQ4BX
  • AromasinPTNCI-GLOSSCDR0000508683
  • AromasinBRNCI
  • FCE-24304CNNCI
  • ExemestaneSYDTPNSC0713563
  • ExemestanePTNCI
DEFINITION
  • A synthetic androgen analogue. Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04)NCI
code
  • C1097
sameAs
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