About: Elsamitrucin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Elsamitrucin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Elsamitrucin
UMLS_CUI
  • C0059041
CAS_Registry
  • 97068-30-9
In_Clinical_Trial_For
  • Non-Hodgkins Lymphoma
FDA_UNII_Code
  • ZTV0FOB6NU
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 41409
PDQ_Closed_Trial_Search_ID
  • 41409
Chemical_Formula
  • C33H35NO13
Legacy_Concept_Name
  • Elsamitrucin
FULL_SYN
  • ELSAMITRUCINPTFDAZTV0FOB6NU
  • Elsamicin ASYNCI
  • ElsamitrucinPTNCI
  • 10-O-ElsaminosylelsarosylchartarinSNNCI
  • Benzo(h)(1)benzopyrano(5,4,3-cde)(1)ebnzopyran-5,12-dione,10((2-O-(2-amino-2,6-dideoxy-3-O-methyl-alpha-D-galactopyranosyl)-6-deoxy-3-C-methyl-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-methylSNNCI
  • ElsamitrucinaSYNCI
  • ElsamitrucineSYNCI
  • ElsamitrucinumSYNCI
  • BBM 2478ACNNCI
  • BMY-28090CNNCI
  • BRN 5214813CNNCI
DEFINITION
  • An heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I and II, resulting in single-strand breaks and inhibition of DNA replication. (NCI04)NCI
code
  • C1080
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