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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cilostazol
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Cilostazol
UMLS_CUI
  • C0055729
CAS_Registry
  • 73963-72-1
FDA_UNII_Code
  • N7Z035406B
Contributing_Source
  • FDA
Chemical_Formula
  • C20H27N5O2
Legacy_Concept_Name
  • Cilostazol
CHEBI_ID
  • CHEBI:31401
FULL_SYN
  • 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinoneSNNCI
  • PletalBRNCI
  • CILOSTAZOLPTFDAN7Z035406B
  • CilostazolPTNCI
DEFINITION
  • A quinolinone derivative and cellular phosphodiesterase inhibitor, more specific for phosphodiesterase III (PDE III). Although the exact mechanism of action of is unknown, cilostazol and its metabolites appears to inhibit PDE III activity, thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. This results in an increase in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation.NCI
code
  • C1051
sameAs
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