About: Zirconium Zr 89 DFO-MSTP2109A     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Zirconium Zr 89 DFO-MSTP2109A
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • Zirconium Zr 89 DFO-MSTP2109A
PDQ_Open_Trial_Search_ID
  • 745657
PDQ_Closed_Trial_Search_ID
  • 745657
FULL_SYN
  • 89Zr-DFO-MSTP2109ASYNCI
  • Zirconium Zr 89 DFO-MSTP2109APTNCI
DEFINITION
  • A radioimmunoconjugate composed of the radioisotope zirconium Zr 89 conjugated to an antibody that targets six transmembrane epithelial antigen of the prostate 1 (STEAP1) that can potentially be used as a prostate cancer tracer during positron emission tomography (PET). Upon administration of zirconium Zr 89 DFO-MSTP2109A, the antibody moiety DFO-MSTP2109A binds to STEAP1 on prostate cancer cells. In turn, Zr 89 allows for the visualization of those cells using PET. STEAP1, a six-transmembrane domain protein, is overexpressed on the surface of prostate cancer cells.NCI
code
  • C104420
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