About: Saccharomyces boulardii Probiotic Supplement     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Saccharomyces boulardii Probiotic Supplement
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Saccharomyces boulardii Probiotic Supplement
NCI_META_CUI
  • CL436874
PDQ_Open_Trial_Search_ID
  • 735160
PDQ_Closed_Trial_Search_ID
  • 735160
FULL_SYN
  • S. boulardii ProbioticSYNCI
  • Saccharomyces boulardii Probiotic SupplementPTNCI
  • FloratilFBNCI
DEFINITION
  • A probiotic containing the non-pathogenic yeast Saccharomyces boulardii with antidiarrheal and potential anti-inflammatory, antimicrobial and immunomodulating activities. As a dietary supplement, S. boulardii may improve digestion and help maintain adequate colonization of the gastrointestinal (GI) tract by modulating the composition of the normal intestinal microflora. During colonization of the GI tract, S. boulardii forms a protective barrier that helps maintain the integrity of the epithelial barrier. This prevents attachment of pathogens to the intestinal mucosa. In addition, this probiotic secretes a protease that binds to and degrades toxins A and B produced by Clostridium difficile, thereby preventing their harmful effects. Dietary supplementation with this bacterium may reduce the secretion of proinflammatory cytokines and may potentiate natural and acquired immunity.NCI
code
  • C102567
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