About: Aerosolized Aldesleukin     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Aerosolized Aldesleukin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • Aerosolized Aldesleukin
NCI_META_CUI
  • CL435912
PDQ_Open_Trial_Search_ID
  • 733682
PDQ_Closed_Trial_Search_ID
  • 733682
FULL_SYN
  • Aerosolized AldesleukinPTNCI
  • Aerosolized Recombinant IL-2SYNCI
DEFINITION
  • An aerosol formulation of aldesleukin, a recombinant form of interleukin-2 (IL-2), with potential immunostimulating activity. Upon IL-2 inhalation, this cytokine activates lymphokine-activated killer cells and natural killer cells, and induces expression of cytotoxic cytokines, such as interferon-gamma and transforming growth factor-beta. This may eventually halt tumor cell growth. Localized administration of IL-2 may decrease toxicity and increase efficacy.NCI
code
  • C101794
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