About: Folate Binding Protein E39 Peptide Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Folate Binding Protein E39 Peptide Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Folate Binding Protein E39 Peptide Vaccine
NCI_META_CUI
  • CL435783
PDQ_Open_Trial_Search_ID
  • 732482
PDQ_Closed_Trial_Search_ID
  • 732482
FULL_SYN
  • FBP E39 Peptide VaccineSYNCI
  • E39 Peptide VaccineSYNCI
  • Folate Binding Protein E39 Peptide VaccinePTNCI
DEFINITION
  • A cancer vaccine comprised of human leukocyte antigen (HLA) A2 restricted folate binding protein (FBP) epitope E39 (amino acids 191 to 199), with potential immunostimulatory and antineoplastic activity. Upon intradermal injection, FBP E39 peptide vaccine may induce a specific cytotoxic T-lymphocyte (CTL) response against FBP-expressing tumor cell types. FBP is a membrane-bound, tumor-associated antigen highly overexpressed in various tumor cell types, such as in breast, ovarian and endometrial cancers; E 39 is a strong immunogenic peptide.NCI
code
  • C101530
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