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About: http://linked.opendata.cz/resource/sukl/spc/sentence/SPC138580_doc-4-5-3-1 Goto Sponge NotDistinct Permalink

An Entity of Type : salt:Sentence, within Data Space : linked.opendata.cz associated with source document(s)

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salt:hasText	Fentanyl, léčivá látka s vysokou clearance, je rychle a extenzivně metabolizován enzymovým systémem CYP3A4. Současné užívání fentanylové transdermální náplasti s inhibitory cytochromu P450 3A4 (CYP3A4) (např. ritonavir, ketokonazol, itrakonazol, flikonazol, vorikonazol, troleandomycin, klarithromycin, nelfinavir, nefazodon, verapamil, diltiazem a amiodaron) může vést ke zvýšení koncentrace fentanylu v plazmě, která by mohla zvýšit nebo prodloužit, jak léčebné, tak nežádoucí účinky a může být příčinou respirační deprese. (cs)
is salt:hasSentence of	http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC138580_doc-4-5-3

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