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salt:hasText	Interakce s léčivými přípravky Je známo, že některé látky zvyšují nebo snižují hladiny cyklosporinu v plazmě nebo celkově v krvi tím, že inhibují nebo indukují enzymy účastnící se metabolizmu cyklosporinu, což se týká zvláště cytochromu P450. Léčivé přípravky, které mohou zvyšovat koncentraci cyklosporinu v krvi tím, že inhibují enzymy odpovědné za jeho metabolizmus a vylučování (především cytochrom P450 IIIA): Perorální antikoncepční prostředky, glukokortikoidy, makrolidová antibiotika (erytromycin, klaritromycin, josamycin), imidazolová a triazolová antimykotika (metronidazol, flukonazol, itrakonazol, ketokonazol), antagonisté H2 receptorů (ranitidin, cimetidin), blokátory kalciových kanálů (diltiazem, nifedipin, nimodipin, nikardipin, verapamil), fluorochinolony, pristinamycin, doxycyklin, propafenon, allopurinol, bromokriptin, danazol, metoklopramid, amiodaron, kyselina ursodeoxycholová, inhibitory proteázy. (cs)
is salt:hasSentence of	http://linked.opendata.cz/resource/sukl/spc/paragraph/SPC115123_doc-4-5-7

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