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  • Dávka hydrochloridu irinotekanu a/nebo 5-FU by se měla snížit o 15 až 20% v těchto případech: hematologická toxicita (neutropenie stupně 4), febrilní neutropenie [neutropenie stupně 3-4 a horečka stupně 2-4], trombocytopenie a leukopenie [stupně 4], nehematologická toxicita [stupně 3-4]. (cs)
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