About: Secukinumab

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A human monoclonal antibody, secukinumab (Cosentyx) was designed for the treatment of uveitis, rheumatoid arthritis, ankylosing spondylitis, and psoriasis. Secukinumab is an interleukin-17A inhibitor marketed by Novartis. On January 19, 2015, secukinumab was approved by the European Commission as a first line systemic treatment in moderate to severe adult plaque psoriasis. On January 21, 2015, the United States Food and Drug Administration announced that it had approved secukinumab to treat adults with moderate-to-severe plaque psoriasis. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B3EE4-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# McInnes IB, Sieper J, Braun J, Emery P, van der Heijde D, Isaacs JD, Dahmen G, Wollenhaupt J, Schulze-Koops H, Kogan J, Ma S, Schumacher MM, Bertolino AP, Hueber W, Tak PP: Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Ann Rheum Dis. 2014 Feb;73(2):349-56. doi: 10.1136/annrheumdis-2012-202646. Epub 2013 Jan 29. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/23361084 (en)
http://linked.open...gy/drugbank/group	approved (en)
sameAs	Secukinumab
Title	Secukinumab (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB09029/identifier/drugbank/DB09029 http://linked.opendata.cz/resource/drugbank/drug/DB09029/identifier/kegg-drug/D09967 http://linked.opendata.cz/resource/drugbank/drug/DB09029/identifier/wikipedia/Secukinumab
http://linked.open...y/drugbank/patent	http://linked.opendata.cz/resource/drugbank/patent/20130202610
http://linked.open.../drugbank/synonym	AIN457 (en)
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B3EE6-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B3EE5-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Secukinumab
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	875356-43-7 (en)

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