About: Clobutinol     Goto   Sponge   NotDistinct   Permalink

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  • Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Studies in 2004 had indicated that clobutinol has the potential to prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients. (en)
http://linked.open...generalReferences
  • # Bellocq C, Wilders R, Schott JJ, Louerat-Oriou B, Boisseau P, Le Marec H, Escande D, Baro I: A common antitussive drug, clobutinol, precipitates the long QT syndrome 2. Mol Pharmacol. 2004 Nov;66(5):1093-102. Epub 2004 Jul 27. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15280442 # "Boehringer Ingelheim voluntarily withdraws its clobutinol containing medications.". Boehringer Ingelheim. 2007-08-31. (en)
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  • withdrawn (en)
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Title
  • Clobutinol (en)
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http://linked.open...ynthesisReference
  • U.S. Patent 3,121,087. (en)
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  • 14860-49-2 (en)
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