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  • beta-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and as such is an inducer of such detoxification enzymes as cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). β-Naphthoflavone is a putative chemopreventive agent. (en)
http://linked.open...generalReferences
  • # Chlouchi A, Girard C, Bonet A, Viollon-Abadie C, Heyd B, Mantion G, Martin H, Richert L: Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture. Planta Med. 2007 Jul;73(8):742-7. Epub 2007 Jun 28. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17599282 # Izzotti A, Bagnasco M, Cartiglia C, Longobardi M, Camoirano A, Tampa E, Lubet RA, De Flora S: Modulation of multigene expression and proteome profiles by chemopreventive agents. Mutat Res. 2005 Dec 11;591(1-2):212-23. Epub 2005 Aug 3. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/16083920 (en)
http://linked.open...gy/drugbank/group
  • experimental (en)
sameAs
Title
  • beta-Naphthoflavone (en)
adms:identifier
http://linked.open.../drugbank/synonym
  • 5,6-benzoflavone (en)
  • beta-NF (en)
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http://linked.open...gy/drugbank/InChI
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  • 6051-87-2 (en)
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  • (en)
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