About: Tyloxapol

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Tyloxapol is a non-ionic detergent often used as a surfactant. (en)
http://linked.open...generalReferences	# Bhatia AJ, Wade GN: Effects of pregnancy and ovarian steroids on fatty acid synthesis and uptake in Syrian hamsters. Am J Physiol. 1991 Jan;260(1 Pt 2):R153-8. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/1992816 (en)
http://linked.open...gy/drugbank/group	approved (en) investigational (en)
http://linked.open...ugbank/indication	Used as a surfactant to aid liquefaction and removal of mucopurulent (containing mucus and pus) bronchopulmonary secretions, administered by inhalation through a nebulizer or with a stream of oxygen. Also investigated for use/treatment in cystic fibrosis and pediatric indications. (en)
sameAs	Tyloxapol Tyloxapol
Title	Tyloxapol (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB06439/identifier/chemspider/11052515 http://linked.opendata.cz/resource/drugbank/drug/DB06439/identifier/drugbank/DB06439 http://linked.opendata.cz/resource/drugbank/drug/DB06439/identifier/kegg-drug/D03261 http://linked.opendata.cz/resource/drugbank/drug/DB06439/identifier/pharmgkb/PA164743726 http://linked.opendata.cz/resource/drugbank/drug/DB06439/identifier/wikipedia/Tyloxapol
http://linked.open...mechanismOfAction	Tyloxapol, when injected IP, blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. It has also been shown to be inhibitor of lipoprotein lipase, thus preventing triglyceride uptake. (en)
http://linked.open...drugbank/packager	Alcon Laboratories
http://linked.open...drugbank/toxicity	Acute oral LD50 in 1000 mg/kg in mouse and 5000 mg/kg in rat. (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0067043
foaf:page	http://www.drugs.com/ingredient/tyloxapol.html
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B4C9F-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Tyloxapol
http://linked.open...drugbank/InChIKey	http://linked.opendata.cz/resource/drugbank/property/271B4CA0-363D-11E5-9242-09173F13E4C5
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	25301-02-4 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Catapres-tts 1 patch

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