About: lidocaine patch     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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  • The lidocaine patch is composed of an adhesive material containing 5% lidocaine that is applied to a polyester felt backing. When it is applied to the skin, lidocaine is released into the epidermal and dermal layers of the skin, reducing pain at the site of the dysfunctional nerves damaged by the prior herpes zoster infection. The lidocaine patch provides pain reduction without numbness of the affected skin. (en)
http://linked.open...generalReferences
  • # Geha PY, Baliki MN, Chialvo DR, Harden RN, Paice JA, Apkarian AV: Brain activity for spontaneous pain of postherpetic neuralgia and its modulation by lidocaine patch therapy. Pain. 2007 Mar;128(1-2):88-100. Epub 2006 Oct 25. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17067740 # Hines R, Keaney D, Moskowitz MH, Prakken S: Use of lidocaine patch 5% for chronic low back pain: a report of four cases. Pain Med. 2002 Dec;3(4):361-5. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15099246 (en)
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  • investigational (en)
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  • Investigated for use/treatment in pain (acute or chronic). (en)
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Title
  • lidocaine patch (en)
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http://linked.open...mechanismOfAction
  • The lidocaine patch relieves pain and discomfort by blocking signals sent to nerve endings in the skin. Almost 20% of the one million Americans who develop shingles yearly experience long-term pain after the infection has resolved. People over age 60 are especially prone to postherpetic neuralgia. (en)
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