About: Clioquinol

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About: Clioquinol Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Clioquinol was withdrawn in 1983 due to neurotoxicity. (en)
http://linked.open...generalReferences	# Rohde W, Mikelens P, Jackson J, Blackman J, Whitcher J, Levinson W: Hydroxyquinolines inhibit ribonucleic acid-dependent deoxyribonucleic acid polymerase and inactivate Rous sarcoma virus and herpes simplex virus. Antimicrob Agents Chemother. 1976 Aug;10(2):234-40. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/185949 # GHOLZ LM, ARONS WL: PROPHYLAXIS AND THERAPY OF AMEBIASIS AND SHIGELLOSIS WITH IODOCHLORHYDROXYQUIN. Am J Trop Med Hyg. 1964 May;13:396-401. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/14162901 # Kager PA: [Outbreak of amoebiasis in a Dutch family; tropics unexpectedly nearby] Ned Tijdschr Geneeskd. 2005 Jan 1;149(1):51-2; author reply 52-3. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15651505 # Bosman DK, Benninga MA, van de Berg P, Kooijman GC, van Gool T: [Dientamoeba fragilis: possibly an important cause of persistent abdominal pain in children] Ned Tijdschr Geneeskd. 2004 Mar 20;148(12):575-9. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15074181 # Masters DK, Hopkins AD: Therapeutic trial of four amoebicide regimes in rural Zaire. J Trop Med Hyg. 1979 May;82(5):99-101. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/226725 (en)
http://linked.open...gy/drugbank/group	withdrawn (en)
http://linked.open...ugbank/indication	Used as a topical antifungal treatment. (en)
sameAs	Clioquinol Clioquinol
Title	Clioquinol (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB04815/identifier/chemspider/2686 http://linked.opendata.cz/resource/drugbank/drug/DB04815/identifier/drugbank/DB04815 http://linked.opendata.cz/resource/drugbank/drug/DB04815/identifier/pharmgkb/PA449039 http://linked.opendata.cz/resource/drugbank/drug/DB04815/identifier/pubchem-compound/2788 http://linked.opendata.cz/resource/drugbank/drug/DB04815/identifier/pubchem-substance/46509081 http://linked.opendata.cz/resource/drugbank/drug/DB04815/identifier/wikipedia/Clioquinol
http://linked.open...mechanismOfAction	Clioquinol is bacteriostatic, however, the precise mechanism of its action is unknown. (en)
http://linked.open.../drugbank/synonym	5-Chloro-7-iodo-8-hydroxyquinoline (en) 5-Chloro-7-iodo-8-quinolinol (en) 5-Chloro-8-hydroxy-7-iodoquinoline (en) 7-Iodo-5-chloro-8-hydroxyquinoline (en) 7-Iodo-5-chloroxine (en) Chloroiodoquin (en) Iodochlorhydroxyquin (en) Iodochlorhydroxyquinoline (en) Iodochlorohydroxyquin (en) Iodochloroxyquinoline (en) 5-Chlor-7-jod-8-hydroxy-chinolin (en) 5-chloro-7-iodoquinolin-8-ol (en) Clioquinolum (en)
http://linked.open.../drugbank/mixture	Avalide 300/12.5 mg
http://linked.open...ynthesisReference	"DrugSyn.org":http://www.drugsyn.org/Clioquinol.htm (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0011656
foaf:page	http://www.drugs.com/mtm/clioquinol-topical.html
http://linked.open...ugbank/IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B560D-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B5613-363D-11E5-9242-09173F13E4C5
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B5612-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B560F-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B5610-363D-11E5-9242-09173F13E4C5
http://linked.open...y/drugbank/SMILES	http://linked.opendata.cz/resource/drugbank/property/271B5611-363D-11E5-9242-09173F13E4C5
http://linked.open.../Water-Solubility	http://linked.opendata.cz/resource/drugbank/property/271B560B-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logP	http://linked.opendata.cz/resource/drugbank/property/271B5609-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B560C-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logS	http://linked.opendata.cz/resource/drugbank/property/271B560A-363D-11E5-9242-09173F13E4C5
http://linked.open...nd-Acceptor-Count	http://linked.opendata.cz/resource/drugbank/property/271B5619-363D-11E5-9242-09173F13E4C5
http://linked.open...-Bond-Donor-Count	http://linked.opendata.cz/resource/drugbank/property/271B561A-363D-11E5-9242-09173F13E4C5
http://linked.open...drugbank/InChIKey	http://linked.opendata.cz/resource/drugbank/property/271B5614-363D-11E5-9242-09173F13E4C5
http://linked.open...urface-Area--PSA-	http://linked.opendata.cz/resource/drugbank/property/271B5615-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/Polarizability	http://linked.opendata.cz/resource/drugbank/property/271B5617-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Refractivity	http://linked.opendata.cz/resource/drugbank/property/271B5616-363D-11E5-9242-09173F13E4C5
http://linked.open...atable-Bond-Count	http://linked.opendata.cz/resource/drugbank/property/271B5618-363D-11E5-9242-09173F13E4C5
http://linked.open...ugbank/absorption	Topical absorption is rapid and extensive, especially when the skin is covered with an occlusive dressing or if the medication is applied to extensive or eroded areas of the skin. Clioquinol is absorbed through the skin in sufficient amounts to affect thyroid function tests. (en)
http://linked.open...casRegistryNumber	130-26-7 (en)
http://linked.open...k/Bioavailability	http://linked.opendata.cz/resource/drugbank/property/271B561F-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Ghose-Filter	http://linked.opendata.cz/resource/drugbank/property/271B5621-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/MDDR-Like-Rule	http://linked.opendata.cz/resource/drugbank/property/271B5622-363D-11E5-9242-09173F13E4C5
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B5623-363D-11E5-9242-09173F13E4C5
http://linked.open...k/Number-of-Rings	http://linked.opendata.cz/resource/drugbank/property/271B561E-363D-11E5-9242-09173F13E4C5
http://linked.open...siological-Charge	http://linked.opendata.cz/resource/drugbank/property/271B561D-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Rule-of-Five	http://linked.opendata.cz/resource/drugbank/property/271B5620-363D-11E5-9242-09173F13E4C5
http://linked.open...tional-IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B560E-363D-11E5-9242-09173F13E4C5
http://linked.open...strongest-acidic-	http://linked.opendata.cz/resource/drugbank/property/271B561B-363D-11E5-9242-09173F13E4C5
http://linked.open...-strongest-basic-	http://linked.opendata.cz/resource/drugbank/property/271B561C-363D-11E5-9242-09173F13E4C5

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