About: 9-(4-hydroxybutyl)-N2-phenylguanine     Goto   Sponge   NotDistinct   Permalink

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  • 9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine is known to target thymidine kinase. (en)
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  • # Kaufman HE, Varnell ED, Wright GE, Xu H, Gebhardt BM, Thompson HW: Effect of 9-(4-hydroxybutyl)-N2-phenylguanine (HBPG), a thymidine kinase inhibitor, on clinical recurrences of ocular herpetic keratitis in squirrel monkeys. Antiviral Res. 1996 Dec;33(1):65-72. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8955854 # Gebhardt BM, Focher F, Eberle R, Manikowski A, Wright GE: Effect of combinations of antiviral drugs on herpes simplex encephalitis. Drug Des Devel Ther. 2009 Dec 29;3:289-94. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/20054446 (en)
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  • experimental (en)
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Title
  • 9-(4-hydroxybutyl)-N2-phenylguanine (en)
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  • HBPG (en)
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