About: Sulfamethazine

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Sulfamethazine Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides. [PubChem] (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...ugbank/indication	For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections. (en)
sameAs	Sulfamethazine Sulfamethazine
Title	Sulfamethazine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB01582/identifier/chebi/102265 http://linked.opendata.cz/resource/drugbank/drug/DB01582/identifier/chemspider/5136 http://linked.opendata.cz/resource/drugbank/drug/DB01582/identifier/drugbank/DB01582 http://linked.opendata.cz/resource/drugbank/drug/DB01582/identifier/pharmgkb/PA451542 http://linked.opendata.cz/resource/drugbank/drug/DB01582/identifier/pubchem-compound/5327 http://linked.opendata.cz/resource/drugbank/drug/DB01582/identifier/pubchem-substance/46507146
http://linked.open...mechanismOfAction	Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides. (en)
http://linked.open...drugbank/packager	C.O. Truxton Inc. Nucare Pharmaceuticals Inc.
http://linked.open.../drugbank/synonym	Sulfadimidine (en) 4-Amino-N-(4,6-dimethyl-pyrimidin-2-yl)-benzenesulfonamide (en) (P-Aminobenzolsulfonyl)-2-amino-4,6-dimethylpyrimidin (en) 2-Sulfanilamido-4,6-dimethylpyrimidine (en) 4,6-Dimethyl-2-sulfanilamidopyrimidine (en) N(1)-(4,6-Dimethyl-2-pyrimidinyl)sulfanilamide (en) N(1)-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide (en) N-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide (en) 4-amino-N-(4,6-Dimethylpyrimidin-2-yl)benzenesulfonamide (en) SMZ (en) Sulfadimethyldiazine (en) Sulfadimethylpyrimidine (en) Sulfadimidina (en) Sulfadimidinum (en) Sulfametazina (en) Sulfametazyny (en) Sulfamezathine (en) Sulphadimethylpyrimidine (en) Sulphamethazine (en) 2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine (en) 6-(4'-Aminobenzol-sulfonamido)-2,4-dimethylpyrimidin (en) 2-(P-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine (en) 4-Amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide (en)
http://linked.open...drugbank/toxicity	Sulfamethazine may cause nausea, vomiting, diarrhea and hypersensitivity reactions. Hematologic effects such as anemia, agranulocytosis, thrombocytopenia and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency may also occur. Sulfamethoxazole may displace bilirubin from albumin binding sites causing jaundice or kernicterus in newborns. (en)
http://linked.open...k/foodInteraction	Do not take calcium, aluminium, magnesium or iron supplements within 2 hours of taking this medication. (en)
http://linked.open...ugbank/IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B5817-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B581D-363D-11E5-9242-09173F13E4C5
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B581C-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B5819-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B581A-363D-11E5-9242-09173F13E4C5
http://linked.open...y/drugbank/SMILES	http://linked.opendata.cz/resource/drugbank/property/271B581B-363D-11E5-9242-09173F13E4C5
http://linked.open.../Water-Solubility	http://linked.opendata.cz/resource/drugbank/property/271B582D-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B5815-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logP	http://linked.opendata.cz/resource/drugbank/property/271B582F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B5813-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B5816-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logS	http://linked.opendata.cz/resource/drugbank/property/271B5814-363D-11E5-9242-09173F13E4C5
http://linked.open...logy/drugbank/pKa	http://linked.opendata.cz/resource/drugbank/property/271B5830-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Sulfadimidine
http://linked.open...nd-Acceptor-Count	http://linked.opendata.cz/resource/drugbank/property/271B5823-363D-11E5-9242-09173F13E4C5
http://linked.open...-Bond-Donor-Count	http://linked.opendata.cz/resource/drugbank/property/271B5824-363D-11E5-9242-09173F13E4C5
http://linked.open...drugbank/InChIKey	http://linked.opendata.cz/resource/drugbank/property/271B581E-363D-11E5-9242-09173F13E4C5
http://linked.open...urface-Area--PSA-	http://linked.opendata.cz/resource/drugbank/property/271B581F-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/Polarizability	http://linked.opendata.cz/resource/drugbank/property/271B5821-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Refractivity	http://linked.opendata.cz/resource/drugbank/property/271B5820-363D-11E5-9242-09173F13E4C5
http://linked.open...atable-Bond-Count	http://linked.opendata.cz/resource/drugbank/property/271B5822-363D-11E5-9242-09173F13E4C5
http://linked.open...ugbank/absorption	Rapidly absorbed following oral administration. (en)
http://linked.open...casRegistryNumber	57-68-1 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Nasacort aq nasal spray
http://linked.open...k/Bioavailability	http://linked.opendata.cz/resource/drugbank/property/271B5829-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Ghose-Filter	http://linked.opendata.cz/resource/drugbank/property/271B582B-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/MDDR-Like-Rule	http://linked.opendata.cz/resource/drugbank/property/271B582C-363D-11E5-9242-09173F13E4C5
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B582E-363D-11E5-9242-09173F13E4C5
http://linked.open...k/Number-of-Rings	http://linked.opendata.cz/resource/drugbank/property/271B5828-363D-11E5-9242-09173F13E4C5
http://linked.open...siological-Charge	http://linked.opendata.cz/resource/drugbank/property/271B5827-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Rule-of-Five	http://linked.opendata.cz/resource/drugbank/property/271B582A-363D-11E5-9242-09173F13E4C5
http://linked.open...tional-IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B5818-363D-11E5-9242-09173F13E4C5
http://linked.open...strongest-acidic-	http://linked.opendata.cz/resource/drugbank/property/271B5825-363D-11E5-9242-09173F13E4C5
http://linked.open...-strongest-basic-	http://linked.opendata.cz/resource/drugbank/property/271B5826-363D-11E5-9242-09173F13E4C5

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 41 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software