About: Practolol     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias. [PubChem] (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...ugbank/indication
  • Used in the emergency treatment of cardiac arrhythmias. (en)
sameAs
Title
  • Practolol (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Like other beta-adrenergic antagonists, practolol competes with adrenergic neurotransmitters such as catecholamines for binding at sympathetic receptor sites. Like propranolol and timolol, practolol binds at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting the effects of the catecholamines epinephrine and norepinephrine and decreasing heart rate, cardiac output, and systolic and diastolic blood pressure. (en)
http://linked.open.../drugbank/synonym
  • Tocris-0831 (en)
  • (+-)-Practolol (en)
  • 1-(4-Acetamidophenoxy)-3-isopropylamino-2-propanol (en)
  • Practololum (en)
  • N-(4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide (en)
  • 4'-(2-Hydroxy-3-(isopropylamino)propoxy)acetanilide (en)
http://linked.open...drugbank/toxicity
  • Symptoms of overdose include abdominal irritation, central nervous system depression, coma, extremely slow heartbeat, heart failure, lethargy, low blood pressure, and wheezing. (en)
http://linked.open...k/foodInteraction
  • Avoid alcohol. (en)
  • Avoid natural licorice. (en)
http://linked.open...y/mesh/hasConcept
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open...aco2-Permeability
http://linked.open...casRegistryNumber
  • 6673-35-4 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...strongest-acidic-
http://linked.open...-strongest-basic-
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