About: Calcium Chloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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  • Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement. It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers. [Wikipedia] (en)
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  • approved (en)
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  • For the treatment of hypocalcemia in those conditions requiring a prompt increase in blood plasma calcium levels, for the treatment of magnesium intoxication due to overdosage of magnesium sulfate, and used to combat the deleterious effects of hyperkalemia as measured by electrocardiographic (ECG), pending correction of the increased potassium level in the extracellular fluid. (en)
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Title
  • Calcium Chloride (en)
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http://linked.open...mechanismOfAction
  • Calcium chloride in water dissociates to provide calcium (Ca<sup>2+</sup>) and chloride (Cl<sup>-</sup>) ions. They are normal constituents of the body fluids and are dependent on various physiological mechanisms for maintenance of balance between intake and output. For hyperkalemia, the influx of calcium helps restore the normal gradient between threshold potential and resting membrane potential. (en)
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  • Approximately 80% of body calcium is excreted in the feces as insoluble salts; urinary excretion accounts for the remaining 20%. (en)
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  • Calcium chloride anhydrous (en)
  • CaCl2 (en)
  • [CaCl2] (en)
http://linked.open...drugbank/toxicity
  • Too rapid injection may produce lowering of blood pressure and cardiac syncope. Persistent hypercalcemia from overdosage of calcium is unlikely because of rapid excretion. (en)
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  • (en)
http://linked.open...ynthesisReference
  • Silvano Grosso, Kenneth E. Nelson, "Method for preparing liquid feed supplements containing calcium chloride." U.S. Patent US3962484, issued August, 1973. (en)
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  • Humans and other mammals (en)
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  • 14639-81-7 (en)
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  • (en)
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