| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. [PubChem] (en)
|
| http://linked.open...y/drugbank/dosage
| |
| http://linked.open...generalReferences
| - * "MSDS":http://msds.orica.com/pdf/shess-en-cds-010-000000033835.pdf (en)
|
| http://linked.open...gy/drugbank/group
| |
| http://linked.open...drugbank/halfLife
| |
| http://linked.open...ugbank/indication
| - For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever. (en)
|
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - Chlorpheniramine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. (en)
|
| http://linked.open...drugbank/packager
| |
| http://linked.open.../drugbank/synonym
| - Chlorphenamine (en)
- Chlorpheniramine (en)
- Haynon (en)
- Chlorophenylpyridamine (en)
- Clorfeniramina (en)
- γ-(4-chlorophenyl)-γ-(2-pyridyl)propyldimethylamine (en)
- Chlorphenamin (en)
- Chlorphenaminum (en)
- Chlorpheniraminum (en)
- Clofeniramina (en)
- Clorfenamina (en)
- 2-[P-chloro-alpha-[2-(dimethylamino)Ethyl]benzyl]pyridine (en)
- 1-(P-Chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine (en)
- gamma-(4-Chlorophenyl)-gamma-(2-pyridyl)propyldimethylamine (en)
- gamma-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine (en)
- 3-(P-Chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine (en)
- 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane (en)
|
| http://linked.open...drugbank/toxicity
| - Oral LD50 (rat): 306 mg/kg; Oral LD50 (mice): 130 mg/kg; Oral LD50 (guinea pig): 198 mg/kg [Registry of Toxic Effects of Chemical Substances. Ed. D. Sweet, US Dept. of Health & Human Services: Cincinatti, 2010.] Also a mild reproductive toxin to women of childbearing age. (en)
|
| http://linked.open.../drug/hasAHFSCode
| |
| http://linked.open...k/foodInteraction
| - Avoid alcohol. (en)
- Take with food. (en)
|
| http://linked.open.../drugbank/mixture
| |
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