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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type
http://linked.open...gbank/description
  • A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion. [PubChem] (en)
http://linked.open...y/drugbank/dosage
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • 2.5-3.5 hours (en)
http://linked.open...ugbank/indication
  • For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Famotidine (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Famotidine binds competitively to H<sub>2</sub>-receptors located on the basolateral membrane of the parietal cell, blocking histamine affects. This competitive inhibition results in reduced basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. (en)
http://linked.open...drugbank/packager
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