About: Ceforanide

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Ceforanide Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Ceforanide is a second-generation parenteral cephalosporin antibiotic. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, a second-generation cephalosporin, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species. (en)
http://linked.open...generalReferences	# Crowle AJ, Sbarbaro JA, May MH: Effects of isoniazid and of ceforanide against virulent tubercle bacilli in cultured human macrophages. Tubercle. 1988 Mar;69(1):15-25. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/3140456 # Campoli-Richards DM, Lackner TE, Monk JP: Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. Drugs. 1987 Oct;34(4):411-37. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/3315624 # Cone LA, Barton SM, Woodard DR: Treatment of scleroma with ceforanide. Arch Otolaryngol Head Neck Surg. 1987 Apr;113(4):374-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/3814386 # Barriere SL, Mills J: Ceforanide: antibacterial activity, pharmacology, and clinical efficacy. Pharmacotherapy. 1982 Nov-Dec;2(6):322-7. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/6762529 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	2.6 to 2.98 hours (en)
http://linked.open...ugbank/indication	For the treatment of infections caused by susceptible organisms. (en)
http://linked.open...bank/manufacturer	Apothecon inc div bristol myers squibb Bristol laboratories inc div bristol myers co
sameAs	Ceforanide Ceforanide
Title	Ceforanide (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/chebi/3495 http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/chemspider/39656 http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/drugbank/DB00923 http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/kegg-compound/C06884 http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/kegg-drug/D00259 http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/pubchem-compound/43507 http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/pubchem-substance/46504532 http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/pharmgkb/PA164746057 http://linked.opendata.cz/resource/drugbank/drug/DB00923/identifier/wikipedia/Ceforanide
http://linked.open...mechanismOfAction	The bactericidal activity of ceforanide results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). (en)
http://linked.open.../drugbank/synonym	Ceforanide (en) 7-[O-(Aminomethyl)phenylacetamido]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-3-cephem-4-carboxylic acid (en) (6R,7R)-7-[[2-[2-(Aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (en) Ceforanido (en) Ceforanidum (en) 7beta-[2-(Aminomethyl)phenyl]acetamido-3-{[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl-3,4-didehydrocepham-4-carboxylic acid (en)
http://linked.open...drugbank/toxicity	Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions. (en)
http://linked.open...nk/proteinBinding	80.6% (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0059859
http://linked.open...ugbank/IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B6150-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B6156-363D-11E5-9242-09173F13E4C5
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B6155-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B6152-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B6153-363D-11E5-9242-09173F13E4C5
http://linked.open...y/drugbank/SMILES	http://linked.opendata.cz/resource/drugbank/property/271B6154-363D-11E5-9242-09173F13E4C5
http://linked.open.../Water-Solubility	http://linked.opendata.cz/resource/drugbank/property/271B614E-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logP	http://linked.opendata.cz/resource/drugbank/property/271B614C-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B614F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B6166-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logS	http://linked.opendata.cz/resource/drugbank/property/271B614D-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Ceforanide
http://linked.open...nd-Acceptor-Count	http://linked.opendata.cz/resource/drugbank/property/271B615C-363D-11E5-9242-09173F13E4C5
http://linked.open...-Bond-Donor-Count	http://linked.opendata.cz/resource/drugbank/property/271B615D-363D-11E5-9242-09173F13E4C5
http://linked.open...drugbank/InChIKey	http://linked.opendata.cz/resource/drugbank/property/271B6157-363D-11E5-9242-09173F13E4C5
http://linked.open...urface-Area--PSA-	http://linked.opendata.cz/resource/drugbank/property/271B6158-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/Polarizability	http://linked.opendata.cz/resource/drugbank/property/271B615A-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Refractivity	http://linked.opendata.cz/resource/drugbank/property/271B6159-363D-11E5-9242-09173F13E4C5
http://linked.open...atable-Bond-Count	http://linked.opendata.cz/resource/drugbank/property/271B615B-363D-11E5-9242-09173F13E4C5
http://linked.open...ugbank/absorption	Rapidly absorbed following intramuscular injection. (en)
http://linked.open.../affectedOrganism	Enteric bacteria and other eubacteria (en)
http://linked.open...casRegistryNumber	60925-61-3 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...k/Bioavailability	http://linked.opendata.cz/resource/drugbank/property/271B6162-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Ghose-Filter	http://linked.opendata.cz/resource/drugbank/property/271B6164-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/MDDR-Like-Rule	http://linked.opendata.cz/resource/drugbank/property/271B6165-363D-11E5-9242-09173F13E4C5
http://linked.open...k/Number-of-Rings	http://linked.opendata.cz/resource/drugbank/property/271B6161-363D-11E5-9242-09173F13E4C5
http://linked.open...siological-Charge	http://linked.opendata.cz/resource/drugbank/property/271B6160-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Rule-of-Five	http://linked.opendata.cz/resource/drugbank/property/271B6163-363D-11E5-9242-09173F13E4C5
http://linked.open...tional-IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B6151-363D-11E5-9242-09173F13E4C5
http://linked.open...strongest-acidic-	http://linked.opendata.cz/resource/drugbank/property/271B615E-363D-11E5-9242-09173F13E4C5
http://linked.open...-strongest-basic-	http://linked.opendata.cz/resource/drugbank/property/271B615F-363D-11E5-9242-09173F13E4C5

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 26 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software