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  • Bitolterol mesylate is a beta-2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and COPD. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001. [Wikipedia] (en)
http://linked.open...generalReferences
  • # Bierman CW, Kemp JP, Nathan RA: Efficacy and safety of inhaled bitolterol mesylate via metered-dose inhaler in children with asthma. Ann Allergy Asthma Immunol. 1996 Jan;76(1):27-35. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8564625 # Friedel HA, Brogden RN: Bitolterol. A preliminary review of its pharmacological properties and therapeutic efficacy in reversible obstructive airways disease. Drugs. 1988 Jan;35(1):22-41. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/3278878 # Nathan RA, Bronsky EA, Dockhorn RJ, Kemp JP: Multicenter dose-ranging study of bitolterol mesylate solution for nebulization in children with asthma. Ann Allergy. 1994 Mar;72(3):209-16. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/8129213 # Messina MS: Retrospective study of bitolterol mesylate in the treatment of conditions associated with reversible bronchospasm. Adv Ther. 1995 May-Jun;12(3):157-63. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10155050 (en)
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  • withdrawn (en)
http://linked.open...ugbank/indication
  • Used to dilate air passages in the lungs that have become narrowed as a result of disease or inflammation. It is used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). (en)
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sameAs
Title
  • Bitolterol (en)
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http://linked.open...mechanismOfAction
  • Bitolterol is an adrenergic beta-2 agonist. Asthma results from a narrowing of the bronchial tubes. This narrowing is caused by muscle spasm and inflammation within the bronchial tubes. Agonism of the beta-2 adrenergic receptors by bitolterol leads to a relaxation of the smooth muscles surrounding these airway tubes which then increases the diameter and ease of air flow through the tubes. (en)
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  • Bitolterol Mesylate (en)
  • Bitolterolum (en)
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  • Humans and other mammals (en)
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  • 30392-40-6 (en)
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  • (en)
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