About: Sulfapyridine

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About: Sulfapyridine Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed. (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	6-14 hours. (en)
http://linked.open...ugbank/indication	For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum (en)
http://linked.open...bank/manufacturer	Eli lilly and co
sameAs	Sulfapyridine Sulfapyridine
Title	Sulfapyridine (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/bindingdb/50225845 http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/chebi/132842 http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/chemspider/5145 http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/drugbank/DB00891 http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/kegg-drug/D02434 http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/pubchem-compound/5336 http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/pubchem-substance/46506991 http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/pharmgkb/PA164779050 http://linked.opendata.cz/resource/drugbank/drug/DB00891/identifier/wikipedia/Sulfapyridine
http://linked.open...mechanismOfAction	Sulfapyridine is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid by means of processing the substrate para-aminobenzoic acid (PABA). Dihydropteroate synthetase activity is vital in the synthesis of folate, and folate is required for cells to make nucleic acids, such as DNA or RNA. So if DNA molecules cannot be built, the cell cannot divide. (en)
http://linked.open...drugbank/packager	Amend Gruppo Lepetit SPA
http://linked.open.../drugbank/synonym	Sulfapyridine (en) Streptosilpyridine (en) 2-Sulfanilamidopyridin (en) 2-Sulfanilamidopyridine (en) 2-Sulfanilylaminopyridine (en) 2-Sulfapyridine (en) 4-(2-Pyridinylsulfonyl)aniline (en) 4-[(2-Pyridylamino)sulfonyl]aniline (en) N-2-Pyridylsulfanilamide (en) Sulphapyridine (en) 2-(P-Aminobenzenesulphonamido)pyridine (en) 4-Amino-N,2-pyridinylbenzenesulfonamide (en) 4-Amino-N-pyridin-2-yl-benzenesulfonamide (en) N(1)-2-Pyridylsulfanilamide (en) N(1)-Pyridylsulfanilamide (en) Solfapiridina (en) Sulfapiridina (en) Sulfapyridin (en) Sulfapyridinum (en)
http://linked.open...drugbank/toxicity	LD<sub>50</sub> is 15800 mg/kg (orally in rats). (en)
http://linked.open.../drugbank/mixture	Acti-Hemosyn Acti-Hydroxo/Dibencoz 500 + Folic Acid Tab Acti-Multiveg Foot Rot Boluses
http://linked.open...nk/proteinBinding	Approximately 50% bound to plasma proteins. (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0020757
http://linked.open...ugbank/IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B5947-363D-11E5-9242-09173F13E4C5
http://linked.open...gy/drugbank/InChI	http://linked.opendata.cz/resource/drugbank/property/271B594D-363D-11E5-9242-09173F13E4C5
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B594C-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B5949-363D-11E5-9242-09173F13E4C5
http://linked.open...noisotopic-Weight	http://linked.opendata.cz/resource/drugbank/property/271B594A-363D-11E5-9242-09173F13E4C5
http://linked.open...y/drugbank/SMILES	http://linked.opendata.cz/resource/drugbank/property/271B594B-363D-11E5-9242-09173F13E4C5
http://linked.open.../Water-Solubility	http://linked.opendata.cz/resource/drugbank/property/271B5945-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B595D-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logP	http://linked.opendata.cz/resource/drugbank/property/271B5943-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B5946-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B595F-363D-11E5-9242-09173F13E4C5
http://linked.open...ogy/drugbank/logS	http://linked.opendata.cz/resource/drugbank/property/271B5944-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/property/271B5960-363D-11E5-9242-09173F13E4C5
http://linked.open...logy/drugbank/pKa	http://linked.opendata.cz/resource/drugbank/property/271B5961-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Sulfapyridine
http://linked.open...nd-Acceptor-Count	http://linked.opendata.cz/resource/drugbank/property/271B5953-363D-11E5-9242-09173F13E4C5
http://linked.open...-Bond-Donor-Count	http://linked.opendata.cz/resource/drugbank/property/271B5954-363D-11E5-9242-09173F13E4C5
http://linked.open...drugbank/InChIKey	http://linked.opendata.cz/resource/drugbank/property/271B594E-363D-11E5-9242-09173F13E4C5
http://linked.open...urface-Area--PSA-	http://linked.opendata.cz/resource/drugbank/property/271B594F-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/Polarizability	http://linked.opendata.cz/resource/drugbank/property/271B5951-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Refractivity	http://linked.opendata.cz/resource/drugbank/property/271B5950-363D-11E5-9242-09173F13E4C5
http://linked.open...atable-Bond-Count	http://linked.opendata.cz/resource/drugbank/property/271B5952-363D-11E5-9242-09173F13E4C5
http://linked.open...ugbank/absorption	Approximately 60-80% (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	144-83-2 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Sulfapyridine powder
http://linked.open...k/Bioavailability	http://linked.opendata.cz/resource/drugbank/property/271B5959-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Ghose-Filter	http://linked.opendata.cz/resource/drugbank/property/271B595B-363D-11E5-9242-09173F13E4C5
http://linked.open...nk/MDDR-Like-Rule	http://linked.opendata.cz/resource/drugbank/property/271B595C-363D-11E5-9242-09173F13E4C5
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B595E-363D-11E5-9242-09173F13E4C5
http://linked.open...k/Number-of-Rings	http://linked.opendata.cz/resource/drugbank/property/271B5958-363D-11E5-9242-09173F13E4C5
http://linked.open...siological-Charge	http://linked.opendata.cz/resource/drugbank/property/271B5957-363D-11E5-9242-09173F13E4C5
http://linked.open...bank/Rule-of-Five	http://linked.opendata.cz/resource/drugbank/property/271B595A-363D-11E5-9242-09173F13E4C5
http://linked.open...tional-IUPAC-Name	http://linked.opendata.cz/resource/drugbank/property/271B5948-363D-11E5-9242-09173F13E4C5
http://linked.open...strongest-acidic-	http://linked.opendata.cz/resource/drugbank/property/271B5955-363D-11E5-9242-09173F13E4C5
http://linked.open...-strongest-basic-	http://linked.opendata.cz/resource/drugbank/property/271B5956-363D-11E5-9242-09173F13E4C5

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