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rdf:type
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http://linked.open...gbank/description
| - A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital. [PubChem] (en)
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http://linked.open...gy/drugbank/group
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http://linked.open...drugbank/halfLife
| - 34 (range 11-67) hours (en)
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http://linked.open...ugbank/indication
| - For the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy. (en)
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sameAs
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Title
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adms:identifier
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http://linked.open...mechanismOfAction
| - Methylphenobarbital binds at a distinct binding site associated with a Cl<sup>-</sup> ionopore at the GABA<sub>A</sub> receptor, increasing the duration of time for which the Cl<sup>-</sup> ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. (en)
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http://linked.open...drugbank/packager
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http://linked.open.../drugbank/synonym
| - Methylphenobarbital (en)
- Enphenemal (en)
- Mebaral (en)
- Mephobarbital (en)
- Mephobarbitone (en)
- N-Methylphenobarbital (en)
- Methylphenobarbitone (en)
- 5-Ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione (en)
- 1-Methylphenobarbital (en)
- 5-Ethyl-1-methyl-5-phenyl-pyrimidine-2,4,6-trione (en)
- 5-Ethyl-1-methyl-5-phenylbarbituric acid (en)
- Methylphenobarbitalum (en)
- Metilfenobarbital (en)
- Metilfenobarbitale (en)
- Méthylphénobarbital (en)
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http://linked.open.../drugbank/mixture
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http://linked.open...nk/proteinBinding
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http://linked.open...y/mesh/hasConcept
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foaf:page
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http://linked.open...ugbank/IUPAC-Name
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http://linked.open...gy/drugbank/InChI
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http://linked.open...Molecular-Formula
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http://linked.open.../Molecular-Weight
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http://linked.open...noisotopic-Weight
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http://linked.open...y/drugbank/SMILES
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http://linked.open.../Water-Solubility
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http://linked.open...ogy/drugbank/logP
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http://linked.open...ogy/drugbank/logS
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http://linked.open...logy/drugbank/pKa
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http://linked.open...l/drug/hasATCCode
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http://linked.open...nd-Acceptor-Count
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http://linked.open...-Bond-Donor-Count
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http://linked.open...drugbank/InChIKey
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http://linked.open...urface-Area--PSA-
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http://linked.open...nk/Polarizability
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http://linked.open...bank/Refractivity
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http://linked.open...atable-Bond-Count
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http://linked.open...ugbank/absorption
| - Approximately 50% of an oral dose of mephobarbital is absorbed from the gastrointestinal tract. (en)
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http://linked.open.../affectedOrganism
| - Humans and other mammals (en)
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http://linked.open...casRegistryNumber
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http://linked.open...drugbank/category
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http://linked.open...gbank/containedIn
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http://linked.open...k/Bioavailability
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http://linked.open...bank/Ghose-Filter
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http://linked.open...nk/MDDR-Like-Rule
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http://linked.open...ank/Melting-Point
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http://linked.open...k/Number-of-Rings
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http://linked.open...siological-Charge
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http://linked.open...bank/Rule-of-Five
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http://linked.open...tional-IUPAC-Name
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http://linked.open...strongest-acidic-
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