| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - Semisynthetic, broad-spectrum antibiotic derivative of cephalexin. [PubChem] (en)
|
| http://linked.open...y/drugbank/dosage
| |
| http://linked.open...generalReferences
| - # Hebert AA, Sigman ES, Levy ML: Serum sickness-like reactions from cefaclor in children. J Am Acad Dermatol. 1991 Nov;25(5 Pt 1):805-8. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/1802903 # Parra FM, Igea JM, Martin JA, Alonso MD, Lezaun A, Sainz T: Serum sickness-like syndrome associated with cefaclor therapy. Allergy. 1992 Aug;47(4 Pt 2):439-40. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/1456417 (en)
|
| http://linked.open...gy/drugbank/group
| |
| http://linked.open...drugbank/halfLife
| |
| http://linked.open...ugbank/indication
| - For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections. (en)
|
| http://linked.open...bank/manufacturer
| |
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - Cefaclor, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is possible that cefaclor interferes with an autolysin inhibitor. (en)
|
| http://linked.open...drugbank/packager
| |
| http://linked.open...outeOfElimination
| - Approximately 60% to 85% of the drug is excreted unchanged in the urine within 8 hours, the greater portion being excreted within the first 2 hours. (en)
|
| http://linked.open.../drugbank/synonym
| - Cefaclor (en)
- CCL (en)
- Cefaclor anhydrous (en)
- Cephaclor (en)
- Cefacloro (en)
- Cefaclorum (en)
- Céfeaclor (en)
- 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid (en)
|
| http://linked.open...drugbank/toxicity
| - Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting. (en)
|
| http://linked.open.../drug/hasAHFSCode
| |
| http://linked.open...k/foodInteraction
| - Preferably on an empty stomach, not really problematic. (en)
|
| http://linked.open...nk/proteinBinding
| |
| http://linked.open...ynthesisReference
| - Bing L. Wong, Yong-Qiang Shen, Yung-Pin Chen, "Enzymatic production of cefaclor from cephalexin." U.S. Patent US5939299, issued November, 1987. (en)
|
| http://linked.open...y/mesh/hasConcept
| |
| foaf:page
| |
| http://linked.open...ugbank/IUPAC-Name
| |
| http://linked.open...gy/drugbank/InChI
| |
| http://linked.open...Molecular-Formula
| |
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