About: Hexachlorophene     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797) (en)
http://linked.open...y/drugbank/dosage
http://linked.open...gy/drugbank/group
  • approved (en)
  • withdrawn (en)
http://linked.open...ugbank/indication
  • For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful. (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Hexachlorophene (en)
adms:identifier
http://linked.open...mechanismOfAction
  • The primary mechanism of action of hexachlorophene, based on studies with <i>Bacillus megatherium</i>, is to inhibit the membrane-bound part of the electron transport chain, respiratory D-lactate dehydrogenase. It induces leakage, causes protoplast lysis, and inhibits respiration. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • Acigena (en)
  • Almederm (en)
  • Distodin (en)
  • Exofene (en)
  • Gamophen (en)
  • Gamophene (en)
  • Hexabalm (en)
  • Hexafen (en)
  • Hexascrub (en)
  • Hexide (en)
  • Nabac (en)
  • Phisodan (en)
  • Septisol (en)
  • Septofen (en)
  • Steral (en)
  • Steraskin (en)
  • Surofene (en)
  • Tersaseptic (en)
  • Turgex (en)
  • 2,2'-Dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane (en)
  • 2,2'-Methanediylbis(3,4,6-trichlorophenol) (en)
  • Armohex (en)
  • Bis(2-hydroxy-3,5,6-trichlorophenyl)methane (en)
  • Bis(3,5,6-trichloro-2-hydroxyphenyl)methane (en)
  • Esaclorofene (en)
  • Germa-medica (en)
  • Hexa-germ (en)
  • Hexachlorophenum (en)
  • Hexaclorofeno (en)
  • Phiso-scrub (en)
  • Septi-soft (en)
  • Solu-heks (en)
  • Soy-dome (en)
  • Staphene O (en)
  • Ster-zac (en)
  • Surgi-cen (en)
  • Surgi-cin (en)
  • 2,2'-Dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane (en)
  • 2,2',3,3',5,5'-Hexachloro-6,6'-dihydroxydiphenylmethane (en)
http://linked.open...drugbank/toxicity
  • Oral, rat LD<sub>50</sub>: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities. (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open...nk/proteinBinding
  • 92% (en)
http://linked.open...ynthesisReference
  • U.S. Patent 2,250,480 U.S. Patent 2,435,593 U.S. Patent 2,812,365 (en)
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...logy/drugbank/pKa
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 47 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software