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rdf:type
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http://linked.open...gbank/description
| - A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797) (en)
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http://linked.open...y/drugbank/dosage
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http://linked.open...gy/drugbank/group
| - approved (en)
- withdrawn (en)
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http://linked.open...ugbank/indication
| - For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful. (en)
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http://linked.open...bank/manufacturer
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sameAs
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Title
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adms:identifier
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http://linked.open...mechanismOfAction
| - The primary mechanism of action of hexachlorophene, based on studies with <i>Bacillus megatherium</i>, is to inhibit the membrane-bound part of the electron transport chain, respiratory D-lactate dehydrogenase. It induces leakage, causes protoplast lysis, and inhibits respiration. (en)
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http://linked.open...drugbank/packager
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http://linked.open.../drugbank/synonym
| - Acigena (en)
- Almederm (en)
- Distodin (en)
- Exofene (en)
- Gamophen (en)
- Gamophene (en)
- Hexabalm (en)
- Hexafen (en)
- Hexascrub (en)
- Hexide (en)
- Nabac (en)
- Phisodan (en)
- Septisol (en)
- Septofen (en)
- Steral (en)
- Steraskin (en)
- Surofene (en)
- Tersaseptic (en)
- Turgex (en)
- 2,2'-Dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane (en)
- 2,2'-Methanediylbis(3,4,6-trichlorophenol) (en)
- Armohex (en)
- Bis(2-hydroxy-3,5,6-trichlorophenyl)methane (en)
- Bis(3,5,6-trichloro-2-hydroxyphenyl)methane (en)
- Esaclorofene (en)
- Germa-medica (en)
- Hexa-germ (en)
- Hexachlorophenum (en)
- Hexaclorofeno (en)
- Phiso-scrub (en)
- Septi-soft (en)
- Solu-heks (en)
- Soy-dome (en)
- Staphene O (en)
- Ster-zac (en)
- Surgi-cen (en)
- Surgi-cin (en)
- 2,2'-Dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane (en)
- 2,2',3,3',5,5'-Hexachloro-6,6'-dihydroxydiphenylmethane (en)
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http://linked.open...drugbank/toxicity
| - Oral, rat LD<sub>50</sub>: 66 mg/kg. Signs of overdose include anorexia, vomiting, abdominal cramps, diarrhea, dehydration, convulsions, hypotension, and shock, and in several reported instances, fatalities. (en)
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http://linked.open.../drug/hasAHFSCode
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http://linked.open...nk/proteinBinding
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http://linked.open...ynthesisReference
| - U.S. Patent 2,250,480 U.S. Patent 2,435,593 U.S. Patent 2,812,365 (en)
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foaf:page
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http://linked.open...ugbank/IUPAC-Name
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http://linked.open...gy/drugbank/InChI
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http://linked.open...Molecular-Formula
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http://linked.open.../Molecular-Weight
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http://linked.open...noisotopic-Weight
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http://linked.open...y/drugbank/SMILES
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http://linked.open.../Water-Solubility
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http://linked.open...ogy/drugbank/logP
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http://linked.open...ogy/drugbank/logS
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http://linked.open...logy/drugbank/pKa
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http://linked.open...l/drug/hasATCCode
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http://linked.open...nd-Acceptor-Count
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http://linked.open...-Bond-Donor-Count
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http://linked.open...drugbank/InChIKey
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http://linked.open...urface-Area--PSA-
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