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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects. [PubChem] (en)
http://linked.open...y/drugbank/dosage
http://linked.open...generalReferences
  • # Nguewa PA, Fuertes MA, Cepeda V, Iborra S, Carrion J, Valladares B, Alonso C, Perez JM: Pentamidine is an antiparasitic and apoptotic drug that selectively modifies ubiquitin. Chem Biodivers. 2005 Oct;2(10):1387-400. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17191940 (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • 9.1-13.2 hours (en)
http://linked.open...ugbank/indication
  • For the treatment of pneumonia due to <i>Pneumocystis carinii</i>. (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Pentamidine (en)
adms:identifier
http://linked.open...mechanismOfAction
  • The mode of action of pentamidine is not fully understood. It is thought that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids, and proteins. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • Pentamidine (en)
  • Pentamidin (en)
  • 1,5-Bis(4-amidinophenoxy)pentane (en)
  • 4,4'-(Pentamethylenedioxy)dibenzamidine (en)
  • 4,4'-Diamidinodiphenoxypentane (en)
  • P,P'-(pentamethylenedioxy)dibenzamidine (en)
  • Pentamidina (en)
  • Pentamidindiisetionat (en)
  • Pentamidinum (en)
  • 4,4'-(1,5-Pentanediylbis(oxy))bis-benzenecarboximidamide (en)
http://linked.open...drugbank/toxicity
  • Symptoms of overdose include pain, nausea, anorexia, hypotension, fever, rash, bad taste in mouth, confusion/hallucinations, dizziness, and diarrhea. (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open...nk/proteinBinding
  • 69% (en)
http://linked.open...ogy/drugbank/salt
  • (en)
http://linked.open...y/mesh/hasConcept
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open...ugbank/absorption
  • Absorbed poorly through the gastrointestinal tract and is usually administered parenterally. (en)
http://linked.open.../affectedOrganism
  • Pneumocystis carinii (en)
http://linked.open...casRegistryNumber
  • 100-33-4 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...-strongest-basic-
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