| Attributes | Values |
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| rdf:type
| |
| http://linked.open...gbank/description
| - A synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception. [PubChem] (en)
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| http://linked.open...y/drugbank/dosage
| |
| http://linked.open...generalReferences
| |
| http://linked.open...gy/drugbank/group
| |
| http://linked.open...drugbank/halfLife
| - 8.51 ± 2.19 (when a single dose is given to healthy women) (en)
|
| http://linked.open...ugbank/indication
| - Norethindrone acetate is indicated for the treatment of secondary amenorrhea, endometriosis, and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer. (en)
|
| http://linked.open...bank/manufacturer
| |
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - Progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH surge. (en)
|
| http://linked.open...drugbank/packager
| |
| http://linked.open...outeOfElimination
| - Norethindrone is excreted in both urine and feces, primarily as metabolites. (en)
|
| http://linked.open.../drugbank/synonym
| - Norethisterone (en)
- Norethindrone (en)
- Camila (en)
- Conludag (en)
- Micronor (en)
- Micronovum (en)
- Norcolut (en)
- Norethisteron (en)
- Noriday (en)
- Norluten (en)
- Norlutin (en)
- Primolut-N (en)
- Utovlan (en)
- (17alpha)-17-Ethynyl-17-hydroxyestra-4,8(14),9-trien-3-one (en)
- 17-Hydroxy-19-nor-17-alpha-pregn-4-en-20-yn-3-one (en)
- 17-Hydroxy-19-nor-17alpha-pregn-4-en-20-yn-3-one (en)
- 17-alpha-Ethynyl-17-hydroxy-4-estren-3-one (en)
- 17-alpha-Ethynyl-19-nortestosterone (en)
- 17-alpha-Ethynyl-4-estren-17-ol-3-one (en)
- 17-beta-Hydroxy-19-norpregn-4-en-20-yn-3-one (en)
- 17alpha-Ethinyl-19-nortestosterone (en)
- 17alpha-Ethinylestra-4-en-17beta-ol-3-one (en)
- 17alpha-Ethynyl-17-hydroxy-4-estren-3-one (en)
- 17alpha-Ethynyl-19-nor-4-androsten-17beta-ol-3-one (en)
- 17alpha-Ethynyl-19-norandrost-4-en-17beta-ol-3-one (en)
- 17alpha-Ethynyl-19-nortestosterone (en)
- 17alpha-Ethynyl-4-estren-17-ol-3-one (en)
- 17beta-Hydroxy-19-norpregn-4-en-20-yn-3-one (en)
- 17α-ethinyl-19-nortestosterone (en)
- 19-Nor-17-alpha-ethynylandrosten-17-beta-ol-3-one (en)
- 19-Nor-17-alpha-ethynyltestosterone (en)
- 19-Nor-17alpha-ethynylandrosten-17beta-ol-3-one (en)
- 19-Nor-17alpha-ethynyltestosterone (en)
|
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