About: Oxacillin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
http://linked.open...gbank/description
  • An antibiotic similar to flucloxacillin used in resistant staphylococci infections. [PubChem] (en)
http://linked.open...y/drugbank/dosage
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • 20 to 30 minutes (en)
http://linked.open...ugbank/indication
  • Used in the treatment of resistant staphylococci infections. (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Oxacillin (en)
adms:identifier
http://linked.open...mechanismOfAction
  • By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Oxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Oxacillin interferes with an autolysin inhibitor. (en)
http://linked.open...drugbank/packager
http://linked.open...outeOfElimination
  • Oxacillin Sodium is rapidly excreted as unchanged drug in the urine by glomerular filtration and active tubular secretion. (en)
http://linked.open.../drugbank/synonym
  • Oxacillin (en)
  • Oxazocilline (en)
  • (2S,5R,6R)-3,3-Dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (en)
  • (5-Methyl-3-phenyl-4-isoxazolyl)penicillin (en)
  • 5-Methyl-3-phenyl-4-isoxazolyl-penicillin (en)
  • 6beta-(5-Methyl-3-phenylisoxazol-4-yl)penicillanic acid (en)
  • Oxacilina (en)
  • Oxacilline (en)
  • Oxacillinum (en)
  • Oxazocillin (en)
http://linked.open.../drugbank/mixture
http://linked.open...nk/proteinBinding
  • 94.2 +/- 2.1% (binds to serum protein, mainly albumin) (en)
http://linked.open...ogy/drugbank/salt
  • (en)
http://linked.open...y/mesh/hasConcept
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...logy/drugbank/pKa
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open.../affectedOrganism
  • Enteric bacteria and other eubacteria (en)
  • Staphylococcus aureus (en)
http://linked.open...casRegistryNumber
  • 66-79-5 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
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