About: Propranolol

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	A widely used non-cardioselective beta-adrenergic antagonist. Propranolol is used in the treatment or prevention of many disorders including acute myocardial infarction, arrhythmias, angina pectoris, hypertension, hypertensive emergencies, hyperthyroidism, migraine, pheochromocytoma, menopause, and anxiety. [PubChem] (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B4B3E-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B3F-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B40-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B41-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B42-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B43-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B44-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B45-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B37-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B38-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B39-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B3A-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B3B-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B3C-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4B3D-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Brunet A, Orr SP, Tremblay J, Robertson K, Nader K, Pitman RK: Effect of post-retrieval propranolol on psychophysiologic responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder. J Psychiatr Res. 2007 Jun 21;. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17588604 # Ohnishi ST, Sadanaga KK, Katsuoka M, Weidanz WP: Effects of membrane acting-drugs on plasmodium species and sickle cell erythrocytes. Mol Cell Biochem. 1989 Nov 23-Dec 19;91(1-2):159-65. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/2695829 # Singh N, Puri SK: Interaction between chloroquine and diverse pharmacological agents in chloroquine resistant Plasmodium yoelii nigeriensis. Acta Trop. 2000 Nov 2;77(2):185-93. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11080509 # Murphy SC, Harrison T, Hamm HE, Lomasney JW, Mohandas N, Haldar K: Erythrocyte G protein as a novel target for malarial chemotherapy. PLoS Med. 2006 Dec;3(12):e528. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17194200 (en)
http://linked.open...gy/drugbank/group	approved (en) investigational (en)
http://linked.open...drugbank/halfLife	4 hours (en)
http://linked.open...ugbank/indication	For the prophylaxis of migraine. (en)
http://linked.open...bank/manufacturer	Advanced Pharmaceutical Services Inc. Diversified Healthcare Services Inc. DSM Corp. Actavis elizabeth llc Inwood laboratories inc sub forest laboratories inc Global Pharmaceuticals Golden State Medical Supply Inc. Amerisource Health Services Corp. AQ Pharmaceuticals Inc. App pharmaceuticals llc Baxter healthcare corp anesthesia critical care Amerifit Inc. Amerisource Health Services Corp. Amkas Laboratories Inc. Amneal Pharmaceuticals Apotheca Inc. Contract Pharm Corepharma LLC CVS Pharmacy Direct Dispensing Inc. Dispensing Solutions Diversified Healthcare Services Inc. Edwards Pharmaceuticals Sandoz H.J. Harkins Co. Inc. Johnson & Johnson Healthcare Kaiser Foundation Hospital Lehigh Valley Technologies Inc. Pfizer Inc. Atlantic Biologicals Corporation Actavis elizabeth llc Apotex inc etobicoke site Breckenridge Pharmaceuticals Ivax pharmaceuticals inc sub teva pharmaceuticals usa Comprehensive Consultant Services Inc. Ivax pharmaceuticals inc sub teva pharmaceuticals usa
sameAs	Propranolol Propranolol
Title	Propranolol (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/bindingdb/25761 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/chebi/8499 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/chemspider/4777 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/drugbank/DB00571 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/guide-to-pharmacology/564 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/iuphar/564 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/kegg-compound/C07407 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/national-drug-code-directory/65726-251-10 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/pubchem-compound/4946 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/pubchem-substance/46505387 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/pharmgkb/PA451145 http://linked.opendata.cz/resource/drugbank/drug/DB00571/identifier/wikipedia/Propranolol
http://linked.open...mechanismOfAction	Propranolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension. (en)
http://linked.open...drugbank/packager	Amend Breckenridge Pharmaceuticals Actavis Group Advanced Pharmaceutical Services Inc. Akrimax Pharmaceuticals Amerisource Health Services Corp. Apotheca Inc. APP Pharmaceuticals A-S Medication Solutions LLC Barr Pharmaceuticals Apotheca Inc. A-S Medication Solutions LLC Ben Venue Laboratories Inc. Bryant Ranch Prepack Caremark LLC Pfizer Inc. Cornerstone Pharmacy Direct Dispensing Inc. Dispensing Solutions Diversified Healthcare Services Inc. Eurand Pharmaceuticals Inc. General Injectables and Vaccines Inc. Sandoz Group Health Cooperative Actavis elizabeth llc American therapeutics inc

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