About: Adenosine triphosphate

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An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
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http://linked.open...gbank/description	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. [PubChem] (en)
http://linked.open...generalReferences	# Gajewski E, Steckler DK, Goldberg RN: Thermodynamics of the hydrolysis of adenosine 5'-triphosphate to adenosine 5'-diphosphate. J Biol Chem. 1986 Sep 25;261(27):12733-7. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/3528161 # Storer AC, Cornish-Bowden A: Concentration of MgATP2- and other ions in solution. Calculation of the true concentrations of species present in mixtures of associating ions. Biochem J. 1976 Oct 1;159(1):1-5. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11772 # Wilson JE, Chin A: Chelation of divalent cations by ATP, studied by titration calorimetry. Anal Biochem. 1991 Feb 15;193(1):16-9. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/1645933 # Garfinkel L, Altschuld RA, Garfinkel D: Magnesium in cardiac energy metabolism. J Mol Cell Cardiol. 1986 Oct;18(10):1003-13. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/3537318 # Parsons M: Glycosomes: parasites and the divergence of peroxisomal purpose. Mol Microbiol. 2004 Aug;53(3):717-24. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15255886 (en)
http://linked.open...gy/drugbank/group	approved (en) nutraceutical (en)
http://linked.open...ugbank/indication	For nutritional supplementation, also for treating dietary shortage or imbalance (en)
sameAs	Adenosine triphosphate Adenosine triphosphate
Title	Adenosine triphosphate (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/bindingdb/2 http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/chebi/15422 http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/drugbank/DB00171 http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/kegg-compound/C00002 http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/pdb/ATP http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/pharmgkb/PA164743471 http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/wikipedia/Adenosine_triphosphate
http://linked.open...mechanismOfAction	ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cellular processes, most typically in mitochondria by oxidative phosphorylation under the catalytic influence of ATP synthase. The total quantity of ATP in the human body is about 0.1 mole. The energy used by human cells requires the hydrolysis of 200 to 300 moles of ATP daily. This means that each ATP molecule is recycled 2000 to 3000 times during a single day. ATP cannot be stored, hence its consumption must closely follow its synthesis. (en)
http://linked.open.../drugbank/synonym	ATP (en) Adenosine 5'-triphosphate (en) Adenosine-5'-triphosphate (en)
http://linked.open...drugbank/toxicity	Oral LD<sub>50</sub> in rats is > 2 g/kg. (en)
http://linked.open...ynthesisReference	George M. Whitesides, Patricia E. Garrett, Merrell G. Siegel, "Method for preparing adenosine triphosphate." U.S. Patent US4164444, issued April, 1975. (en)
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http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	56-65-5 (en)
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