About: L-Cystine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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http://linked.open...gbank/description
  • A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. Two molecules of cysteine are joined together by a disulfide bridge to form cystine. [PubChem] (en)
http://linked.open...gy/drugbank/group
  • approved (en)
  • nutraceutical (en)
http://linked.open...ugbank/indication
  • It has been claimed that L-cysteine has anti-inflammatory properties, that it can protect against various toxins, and that it might be helpful in osteoarthritis and rheumatoid arthritis. More research will have to be done before L-cysteine can be indicated for any of these conditions. Research to date has mostly been in animal models. (en)
sameAs
Title
  • L-Cystine (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Certain conditions, e.g. an acetaminophen overdose, deplete hepatic glutathione and subject the tissues to oxidative stress resulting in loss of cellular integrity. L-Cystine serves as a major precursor for synthesis of glutathione. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • L-Dicysteine (en)
  • L-alpha-Diamino-beta-dithiolactic acid (en)
  • (R,R)-3,3'-dithiobis(2-aminopropanoic acid) (en)
  • β,β'-dithiodialanine (en)
http://linked.open...drugbank/toxicity
  • With typical doses of 1 to 1.5 grams daily, the most commonly reported side effects have been gastrointestinal, such as nausea. There are rare reports of cystine renal stone formation, Single injections of L-cysteine (0.6-1.5 g/kg) into 4-day-old pups resulted in massive damage to cortical neurons, permanent retinal dystrophy, atrophy of the brain and hyperactivity. (en)
http://linked.open...ynthesisReference
  • Peter Stehle, Peter Furst, Werner Fekl, "N,N'-bis-L-amino acid-L-cystine-peptide containing amino acid preparations for oral parenteral nutrition." U.S. Patent US4968696, issued February, 1964. (en)
http://linked.open...y/mesh/hasConcept
foaf:page
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http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 56-89-3 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
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http://linked.open...strongest-acidic-
http://linked.open...-strongest-basic-
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