| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - Ornithine is an amino acid produced in the urea cycle by the splitting off of urea from arginine. It is a central part of the urea cycle, which allows for the disposal of excess nitrogen. L-Ornithine is a precursor of citrulline and arginine. (en)
|
| http://linked.open...gy/drugbank/group
| - approved (en)
- nutraceutical (en)
|
| http://linked.open...ugbank/indication
| - Used for nutritional supplementation, also for treating dietary shortage or imbalance. It has been claimed that ornithine improves athletic performance, has anabolic effects, has wound-healing effects, and is immuno-enhancing. (en)
|
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - L-Ornithine is metabolised to L-arginine. L-arginine stimulates the pituitary release of growth hormone. Burns or other injuries affect the state of L-arginine in tissues throughout the body. As De novo synthesis of L-arginine during these conditions is usually not sufficient for normal immune function, nor for normal protein synthesis, L-ornithine may have immunomodulatory and wound-healing activities under these conditions (by virtue of its metabolism to L-arginine). (en)
|
| http://linked.open.../drugbank/synonym
| - L-Ornithine (en)
- (S)-2,5-Diaminopentanoate (en)
- (S)-2,5-Diaminopentanoic acid (en)
- (S)-2,5-diaminovaleric acid (en)
- (S)-ornithine (en)
- (S)-alpha,delta-Diaminovaleric acid (en)
- (S)-α,δ-diaminovaleric acid (en)
|
| http://linked.open...drugbank/toxicity
| - Oral, rat LD<sub>50</sub> = 10000 mg/kg (en)
|
| http://linked.open...ynthesisReference
| - Takayasu Tsuchida, Haruo Uchibori, Yoshitaka Nishimoto, "Process and microorganism for producing L-ornithine by Corynebacterium, Brevibacterium, or Athrobacter." U.S. Patent US5188947, issued January, 1970. (en)
|
| foaf:page
| |
| http://linked.open...ugbank/IUPAC-Name
| |
| http://linked.open...gy/drugbank/InChI
| |
| http://linked.open...Molecular-Formula
| |
| http://linked.open.../Molecular-Weight
| |
| http://linked.open...noisotopic-Weight
| |
| http://linked.open...y/drugbank/SMILES
| |
| http://linked.open.../Water-Solubility
| |
| http://linked.open...ogy/drugbank/logP
| |
| http://linked.open...ogy/drugbank/logS
| |
| http://linked.open...logy/drugbank/pKa
| |
| http://linked.open...nd-Acceptor-Count
| |
| http://linked.open...-Bond-Donor-Count
| |
| http://linked.open...drugbank/InChIKey
| |
| http://linked.open...urface-Area--PSA-
| |
| http://linked.open...nk/Polarizability
| |
| http://linked.open...bank/Refractivity
| |
| http://linked.open...atable-Bond-Count
| |
| http://linked.open...ugbank/absorption
| - Absorbed from the small intestine via a sodium-dependent active transport process (en)
|
| http://linked.open.../affectedOrganism
| - Humans and other mammals (en)
|
| http://linked.open...casRegistryNumber
| |
| http://linked.open...drugbank/category
| |
| http://linked.open...k/Bioavailability
| |
| http://linked.open...bank/Ghose-Filter
| |
| http://linked.open...nk/MDDR-Like-Rule
| |
| http://linked.open...ank/Melting-Point
| |
| http://linked.open...k/Number-of-Rings
| |
| http://linked.open...siological-Charge
| |
| http://linked.open...bank/Rule-of-Five
| |
| http://linked.open...tional-IUPAC-Name
| |
| http://linked.open...strongest-acidic-
| |
| http://linked.open...-strongest-basic-
| |
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