| Attributes | Values |
|---|
| rdf:type
| |
| http://linked.open...gbank/description
| - A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk. [PubChem] (en)
|
| http://linked.open...generalReferences
| - # Holmberg A, Blomstergren A, Nord O, Lukacs M, Lundeberg J, Uhlen M: The biotin-streptavidin interaction can be reversibly broken using water at elevated temperatures. Electrophoresis. 2005 Feb;26(3):501-10. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15690449 (en)
|
| http://linked.open...gy/drugbank/group
| - approved (en)
- nutraceutical (en)
|
| http://linked.open...ugbank/indication
| - For nutritional supplementation, also for treating dietary shortage or imbalance. (en)
|
| sameAs
| |
| Title
| |
| adms:identifier
| |
| http://linked.open...mechanismOfAction
| - Biotin is necessary for the proper functioning of enzymes that transport carboxyl units and fix carbon dioxide, and is required for various metabolic functions, including gluconeogenesis, lipogenesis, fatty acid biosynthesis, propionate metabolism, and catabolism of branched-chain amino acids. (en)
|
| http://linked.open...drugbank/packager
| |
| http://linked.open.../drugbank/synonym
| - Biotin (en)
- cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid (en)
- Coenzyme R (en)
- D(+)-Biotin (en)
- D-Biotin (en)
- Vitamin B7 (en)
- Vitamin H (en)
- (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid (en)
- Biotina (en)
- Biotine (en)
- Biotinum (en)
- D-(+)-Biotin (en)
- cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid (en)
- 5-(2-Oxohexahydro-1H-thieno[3,4-D]imidazol-4-yl)pentanoic acid (en)
- cis-Tetrahydro-2-oxothieno(3,4-D)imidazoline-4-valeric acid (en)
- (3AS,4S,6ar)-hexahydro-2-oxo-1H-thieno[3,4-D]imidazole-4-valeric acid (en)
|
| http://linked.open...drugbank/toxicity
| - Prolonged skin contact may cause irritation. (en)
|
| http://linked.open.../drug/hasAHFSCode
| |
| http://linked.open...ynthesisReference
| - Takayoshi Mitsunaga, Kiyoto Chinushi, Tadashi Umezu, "Water-soluble biotin-containing preparation." U.S. Patent US4277488, issued May, 1940. (en)
|
| http://linked.open...y/mesh/hasConcept
| |
| foaf:page
| |
| http://linked.open...ugbank/IUPAC-Name
| |
| http://linked.open...gy/drugbank/InChI
| |
| http://linked.open...Molecular-Formula
| |
| http://linked.open.../Molecular-Weight
| |
| http://linked.open...noisotopic-Weight
| |
| http://linked.open...y/drugbank/SMILES
| |
| http://linked.open.../Water-Solubility
| |
| http://linked.open...ogy/drugbank/logP
| |
| http://linked.open...ogy/drugbank/logS
| |
| http://linked.open...l/drug/hasATCCode
| |
| http://linked.open...nd-Acceptor-Count
| |
| http://linked.open...-Bond-Donor-Count
| |
| http://linked.open...drugbank/InChIKey
| |
| http://linked.open...urface-Area--PSA-
| |
| http://linked.open...nk/Polarizability
| |
| http://linked.open...bank/Refractivity
| |
| http://linked.open...atable-Bond-Count
| |
| http://linked.open...ugbank/absorption
| - Systemic - approximately 50% (en)
|
| http://linked.open.../affectedOrganism
| - Humans and other mammals (en)
|
| http://linked.open...casRegistryNumber
| |
| http://linked.open...drugbank/category
| |
| http://linked.open...gbank/containedIn
| |
| http://linked.open...k/Bioavailability
| |
| http://linked.open...bank/Ghose-Filter
| |
| http://linked.open...nk/MDDR-Like-Rule
| |
| http://linked.open...ank/Melting-Point
| |
| http://linked.open...k/Number-of-Rings
| |
| http://linked.open...siological-Charge
| |
| http://linked.open...bank/Rule-of-Five
| |
| http://linked.open...tional-IUPAC-Name
| |
| http://linked.open...strongest-acidic-
| |
| http://linked.open...-strongest-basic-
| |
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