About: Antithymocyte globulin

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Antithymocyte globulin Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells. (en)
http://linked.open...generalReferences	#American Society of Health System Pharmacists, Inc., DynaMed [Internet]. Ipswich (MA): EBSCO Information Services. 1995. Antithymocyte globulin; [updated 2013 Jan 18; cited 2014 Nov 11]; Available http://web.b.ebscohost.com.login.ezproxy.library.ualberta.ca/dynamed/detail?vid=7&sid=78010ea4-6f9c-4d5a-a7df-a148b3891321%40sessionmgr110&hid=123&bdata=JnNpdGU9ZHluYW1lZC1saXZlJnNjb3BlPXNpdGU%3d#db=dme&AN=356335 (en)
http://linked.open...gy/drugbank/group	approved (en)
http://linked.open...drugbank/halfLife	2-3 days, may increase after multiple doses administration (en)
http://linked.open...ugbank/indication	For prevention of renal transplant rejection (en)
sameAs	Antithymocyte globulin Antithymocyte globulin
Title	Antithymocyte globulin (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00098/identifier/drugbank/DB00098 http://linked.opendata.cz/resource/drugbank/drug/DB00098/identifier/pharmgkb/PA164743704
http://linked.open...mechanismOfAction	Binds to multiple, T-cell specific antigens leading to T-lymphocyte cell death via complement mediated cytotoxicity or apoptosis. (en)
http://linked.open...drugbank/packager	Alcon Laboratories
http://linked.open.../drugbank/synonym	Thymoglobulin (en) rATG (en) rabbit ATG (en)
http://linked.open...drugbank/toxicity	Not known whether ATG (rabbit) distributes into human milk; however, other immunoglobulins are distributed into human milk. (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0001465
http://linked.open...ugbank/absorption	T-cell depletion usually observed within 1 day after initiating therapy. Average 21.5 and 87 mcg/mL 4–8 hours post-infusion after first and last IV doses, respectively, when given for 7–11 days. (en)
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	ALPRAZolam Intensol 1 mg/ml Concentrate 30ml Bottle
http://linked.open...ank/Melting-Point	http://linked.opendata.cz/resource/drugbank/property/271B450F-363D-11E5-9242-09173F13E4C5

Faceted Search & Find service v1.16.116 as of Feb 22 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of Feb 22 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 67 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software