About: Hyaluronidase

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About: Hyaluronidase Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/drugbank/Drug
http://linked.open...gbank/description	Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye. (en)
http://linked.open...y/drugbank/dosage	http://linked.opendata.cz/resource/drugbank/dosage/271B4350-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4351-363D-11E5-9242-09173F13E4C5 http://linked.opendata.cz/resource/drugbank/dosage/271B4352-363D-11E5-9242-09173F13E4C5
http://linked.open...generalReferences	# Csoka AB, Scherer SW, Stern R: Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31. Genomics. 1999 Sep 15;60(3):356-61. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10493834 (en)
http://linked.open...gy/drugbank/group	approved (en) investigational (en)
http://linked.open...ugbank/indication	For increase of absorption and distribution of other injected drugs and for rehydration. (en)
http://linked.open...bank/manufacturer	Amphastar pharmaceutical inc Intas Pharmaceuticals Ltd. Ista pharmaceuticals Baxter healthcare corp anesthesia and critical care
sameAs	Hyaluronidase Hyaluronidase
Title	Hyaluronidase (en)
adms:identifier	http://linked.opendata.cz/resource/drugbank/drug/DB00070/identifier/drugbank/DB00070 http://linked.opendata.cz/resource/drugbank/drug/DB00070/identifier/genbank/L13781 http://linked.opendata.cz/resource/drugbank/drug/DB00070/identifier/national-drug-code-directory/0548-9090-10 http://linked.opendata.cz/resource/drugbank/drug/DB00070/identifier/uniprotkb/P38567 http://linked.opendata.cz/resource/drugbank/drug/DB00070/identifier/pharmgkb/PA164745713 http://linked.opendata.cz/resource/drugbank/drug/DB00070/identifier/wikipedia/Hyaluronidase
http://linked.open...mechanismOfAction	Hyaluronidase is a spreading or diffusing substance. It increase the permeability of connective tissue through the hydrolysis of hyaluronic acid. Hyaluronidase hydrolyzes hyaluronic acid by splitting the glucosaminidic bond between C1 of the glucosamine moiety and C4 of glucuronic acid. This temporarily decreases the viscosity of the cellular cement and increases diffusion of injected fluids or of localized transudates or exudates, thus facilitating their absorption. (en)
http://linked.open...drugbank/packager	APP Pharmaceuticals APPD Bausch & Lomb Inc. Baxter International Inc. Cardinal Health Creative Cosmetics Inc. Bristol myers squibb co Dispensing Solutions Ebewe Pharma Generamedix Inc.
http://linked.open.../drugbank/synonym	HYAL-1 (en) Hyaluronidase 1 precursor (en) Hyaluronidase PH-20 (en) Sperm adhesion molecule 1 (en) Sperm surface protein PH-20 (en)
http://linked.open...ynthesisReference	Yasuhiro Mima, Masaaki Yamada, "Preparation of human placental hyaluronidase." U.S. Patent US3945889, issued October, 1957. (en)
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0010666
foaf:page	http://www.drugs.com/cdi/hyaluronidase.html http://www.rxlist.com/cgi/generic/hylenex.htm
http://linked.open...Molecular-Formula	http://linked.opendata.cz/resource/drugbank/property/271B4356-363D-11E5-9242-09173F13E4C5
http://linked.open.../Molecular-Weight	http://linked.opendata.cz/resource/drugbank/property/271B4355-363D-11E5-9242-09173F13E4C5
http://linked.open...l/drug/hasATCCode	Hyaluronidase
http://linked.open.../affectedOrganism	Humans and other mammals (en)
http://linked.open...casRegistryNumber	488712-31-8 (en)
http://linked.open...drugbank/category	(en)
http://linked.open...gbank/containedIn	Hylenex 150 unit/ml vial Hyaluronidase powder Vitrase 6200 unit vial Vitrasert 4.5 mg implant
http://linked.open...nk/Hydrophobicity	http://linked.opendata.cz/resource/drugbank/property/271B4353-363D-11E5-9242-09173F13E4C5
http://linked.open...Isoelectric-Point	http://linked.opendata.cz/resource/drugbank/property/271B4354-363D-11E5-9242-09173F13E4C5

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