About: Hyaluronidase     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type
http://linked.open...gbank/description
  • Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye. (en)
http://linked.open...y/drugbank/dosage
http://linked.open...generalReferences
  • # Csoka AB, Scherer SW, Stern R: Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31. Genomics. 1999 Sep 15;60(3):356-61. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10493834 (en)
http://linked.open...gy/drugbank/group
  • approved (en)
  • investigational (en)
http://linked.open...ugbank/indication
  • For increase of absorption and distribution of other injected drugs and for rehydration. (en)
http://linked.open...bank/manufacturer
sameAs
Title
  • Hyaluronidase (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Hyaluronidase is a spreading or diffusing substance. It increase the permeability of connective tissue through the hydrolysis of hyaluronic acid. Hyaluronidase hydrolyzes hyaluronic acid by splitting the glucosaminidic bond between C1 of the glucosamine moiety and C4 of glucuronic acid. This temporarily decreases the viscosity of the cellular cement and increases diffusion of injected fluids or of localized transudates or exudates, thus facilitating their absorption. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • HYAL-1 (en)
  • Hyaluronidase 1 precursor (en)
  • Hyaluronidase PH-20 (en)
  • Sperm adhesion molecule 1 (en)
  • Sperm surface protein PH-20 (en)
http://linked.open...ynthesisReference
  • Yasuhiro Mima, Masaaki Yamada, "Preparation of human placental hyaluronidase." U.S. Patent US3945889, issued October, 1957. (en)
http://linked.open...y/mesh/hasConcept
foaf:page
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...l/drug/hasATCCode
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 488712-31-8 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...gbank/containedIn
http://linked.open...nk/Hydrophobicity
http://linked.open...Isoelectric-Point
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