About: Satumomab Pendetide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type
http://linked.open...gbank/description
  • Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available. (en)
http://linked.open...generalReferences
  • # Artiko V, Obradovic V, Davidovic B, Petrovic N, Petrovic M, Krivokapic Z, Kecmanovic D, Pesko P, Djukic V, Milosavljevic T, Adanja G, Vlajkovic M: Radioimmunodetection of colorectal carcinoma. Hepatogastroenterology. 2003 Jul-Aug;50(52):1029-31. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12845972 # Bohdiewicz PJ: Indium-111 satumomab pendetide: the first FDA-approved monoclonal antibody for tumor imaging. J Nucl Med Technol. 1998 Sep;26(3):155-63; quiz 170-1. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/ 9755434 (en)
http://linked.open...gy/drugbank/group
  • approved (en)
  • withdrawn (en)
http://linked.open...drugbank/halfLife
  • 0.8 hours (mammalian reticulocytes, in vitro) (en)
http://linked.open...ugbank/indication
  • For diagnosis of extrahepatic malignant cancers (en)
sameAs
Title
  • Satumomab Pendetide (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Satumomab Pendetide is a monoclonal antibody which is attached to the chelator pentetic acid (DTPA) linked to the tripeptide glycine (G) – L-tyrosine (Y) – L-lysine (K), which chelates Indium 111. Satumomab pendetide binds selectively to cell-surface TAG-72 expressed on colorectal tumors. (en)
http://linked.open...drugbank/packager
http://linked.open.../drugbank/synonym
  • Indium (111In) satumomab pendetide (en)
  • Indium-111 satumomab pendetide (en)
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open.../affectedOrganism
  • Humans and other mammals (en)
http://linked.open...casRegistryNumber
  • 138955-26-7 (en)
http://linked.open...drugbank/category
  • (en)
http://linked.open...nk/Hydrophobicity
http://linked.open...Isoelectric-Point
http://linked.open...ank/Melting-Point
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